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Recommended
F1000 Factor 3.0

New Finding
 Helium-induced preconditioning in young and old rat heart: impact of mitochondrial Ca(2+) -sensitive potassium channel activation.
Heinen A, Huhn R, …, Weber NC, Hollmann MW
Anesthesiology 2008 Nov 109(5):830-6 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Zeljko Bosnjak
Evaluated 28 Nov 2008

Must Read
F1000 Factor 6.0

Hypothesis
 Identification of a BK channel auxiliary protein controlling molecular and behavioral tolerance to alcohol.
Martin GE, Hendrickson LM, …, Tapper AR, Treistman SN
Proc Natl Acad Sci U S A 2008 Nov 11 105(45):17543-8 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Gregg Homanics with David Werner
Evaluated 19 Nov 2008

Recommended
F1000 Factor 3.0

Tech Advance
 The effects of varying local anesthetic concentration and volume on continuous popliteal sciatic nerve blocks: a dual-center, randomized, controlled study.
Ilfeld BM, Loland VJ, …, Mariano ER, PAINfRE Investigators
Anesth Analg 2008 Aug 107(2):701-7 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Honorio Benzon with Antoun Nader
Evaluated 13 Nov 2008

Recommended
F1000 Factor 3.0

New Finding
 Alternative translation initiation in rat brain yields K2P2.1 potassium channels permeable to sodium.
Thomas D, Plant LD, …, McCrossan ZA, Goldstein SA
Neuron 2008 Jun 26 58(6):859-70 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Douglas Bayliss
Evaluated 12 Nov 2008

Recommended
F1000 Factor 3.0

Hypothesis
 Intraoperative thoracic epidural anaesthesia attenuates stress-induced immunosuppression in patients undergoing major abdominal surgery.
Ahlers O, Nachtigall I, …, Fritz G, Keh D
Br J Anaesth 2008 Dec 101(6):781-7 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Herbert Koinig
Evaluated 10 Nov 2008

Recommended
F1000 Factor 3.0

Confirmation
 Retrospective evaluation of a computerized physician order entry adaptation to prevent prescribing errors in a pediatric emergency department.
Sard BE, Walsh KE, …, Moschetti W, Bauchner H
Pediatrics 2008 Oct 122(4):782-7 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Alan Merry with Craig Webster
Evaluated 4 Nov 2008

Recommended
F1000 Factor 3.0

New Finding
Controversial
 Postoperative pain and analgesic requirements after anesthesia with sevoflurane, desflurane or propofol.
Fassoulaki A, Melemeni A, …, Siafaka I, Sarantopoulos C
Anesth Analg 2008 Nov 107(5):1715-9 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Martin Angst
Evaluated 3 Nov 2008

Must Read
F1000 Factor 6.0

Confirmation
New Finding
 Isoflurane modulates excitability in the mouse thalamus via GABA-dependent and GABA-independent mechanisms.
Ying SW, Werner DF, …, Harrison NL, Goldstein PA
Neuropharmacology 2008 Oct 9 [abstract on PubMed] [related articles] [full text]
Selected by | M Bruce MacIver
Evaluated 31 Oct 2008

Must Read
F1000 Factor 4.8

New Finding
 Spatial memory is intact in aged rats after propofol anesthesia.
Lee IH, Culley DJ, …, Tanzi RE, Crosby G
Anesth Analg 2008 Oct 107(4):1211-5 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Misha Perouansky / M Bruce MacIver
First evaluation 27 Oct 2008 | Latest evaluation 3 Nov 2008

Recommended
F1000 Factor 3.0

Hypothesis
 Change of AMPA receptors in spinal nociceptive synapses during inflammatory hyperalgesia.
Wang W, Huang J
J Neurosci 2008 Oct 8 28(41):10185-6 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Allan Gottschalk
Evaluated 23 Oct 2008


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