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Must Read
F1000 Factor 6.0

Hypothesis
Remifentanil sedation for awake fibreoptic intubation with limited application of local anaesthetic in patients for elective head and neck surgery.
Mingo OH, Ashpole KJ, Irving CJ, Rucklidge MW
Anaesthesia 2008 Oct 63(10):1065-9 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Peter Farling with Brian Mullan
Evaluated 14 Nov 2008

Must Read
F1000 Factor 6.0

Refutation
Intensive insulin therapy after severe traumatic brain injury: a randomized clinical trial.
Bilotta F, Caramia R, …, Santoro A, Rosa G
Neurocrit Care 2008 9(2):159-66 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Elfyn Thomas with Tod Guest
Evaluated 6 Nov 2008

Recommended
F1000 Factor 3.0

New Finding
Dexmedetomidine weakens dynamic cerebral autoregulation as assessed by transfer function analysis and the thigh cuff method.
Ogawa Y, Iwasaki K, …, Kato J, Ogawa S
Anesthesiology 2008 Oct 109(4):642-50 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Luzius A Steiner with Christoph Burkhart
Evaluated 21 Oct 2008

Exceptional
F1000 Factor 9.0
Articles that inform your practice or change your way of thinking Changes
Clinical Practice

Hypothesis
Subtle neurological abnormalities as risk factors for cognitive and functional decline, cerebrovascular events, and mortality in older community-dwelling adults.
Inzitari M, Pozzi C, …, Marchionni N, Di Bari M
Arch Intern Med 2008 Jun 23 168(12):1270-6 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Philippa Newfield
Evaluated 15 Oct 2008

Recommended
F1000 Factor 3.0

Hypothesis
Diagnosis and initial management of acute stroke and transient ischaemic attack: summary of NICE guidance.
Swain S, Turner C, …, Rudd A, Guideline Development Group
BMJ 2008 337:a786 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Philippa Newfield
Evaluated 8 Oct 2008

Recommended
F1000 Factor 3.0

Hypothesis
Persistent metabolic crisis as measured by elevated cerebral microdialysis lactate-pyruvate ratio predicts chronic frontal lobe brain atrophy after traumatic brain injury.
Marcoux J, McArthur DA, …, Alger JR, Vespa PM
Crit Care Med 2008 Oct 36(10):2871-7 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Arun Gupta
Evaluated 8 Oct 2008

Must Read
F1000 Factor 6.0

New Finding
Effects of propofol on human microcirculation.
Koch M, De Backer D, …, Hennart D, Schmartz D
Br J Anaesth 2008 Oct 101(4):473-8 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Ian Herrick
Evaluated 6 Oct 2008

Recommended
F1000 Factor 3.0

Confirmation
Dosing of remifentanil to prevent movement during craniotomy in the absence of neuromuscular blockade.
Maurtua MA, Deogaonkar A, …, Ebrahim Z, Schubert A
J Neurosurg Anesthesiol 2008 Oct 20(4):221-5 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Dhanesh Gupta
Evaluated 1 Oct 2008

Recommended
F1000 Factor 3.0

Confirmation
New Finding
Amyloid-beta dynamics correlate with neurological status in the injured human brain.
Brody DL, Magnoni S, …, Zipfel GJ, Holtzman DM
Science 2008 Aug 29 321(5893):1221-4 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Vesna Jevtovic-Todorovic
Evaluated 1 Oct 2008

Must Read
F1000 Factor 6.0

Hypothesis
Hospital treatment of patients with ischemic stroke or transient ischemic attack using the "Get With The Guidelines" program.
LaBresh KA, Reeves MJ, …, Albright D, Schwamm LH
Arch Intern Med 2008 Feb 25 168(4):411-7 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Philippa Newfield
Evaluated 30 Sep 2008


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