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Browse > Anesthesiology & Pain Management > Pain: Basic Science
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Recommended
F1000 Factor 3.0

Hypothesis
 Gabapentin attenuates late but not early postoperative pain after thyroidectomy with superficial cervical plexus block.
Brogly N, Wattier JM, …, Vallet B, Lebuffe G
Anesth Analg 2008 Nov 107(5):1720-5 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Patricia Lavand'homme
Evaluated 6 Nov 2008

Recommended
F1000 Factor 3.0

New Finding
Controversial
 Postoperative pain and analgesic requirements after anesthesia with sevoflurane, desflurane or propofol.
Fassoulaki A, Melemeni A, …, Siafaka I, Sarantopoulos C
Anesth Analg 2008 Nov 107(5):1715-9 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Martin Angst
Evaluated 3 Nov 2008

Must Read
F1000 Factor 6.0

Confirmation
New Finding
 Isoflurane modulates excitability in the mouse thalamus via GABA-dependent and GABA-independent mechanisms.
Ying SW, Werner DF, …, Harrison NL, Goldstein PA
Neuropharmacology 2008 Oct 9 [abstract on PubMed] [related articles] [full text]
Selected by | M Bruce MacIver
Evaluated 31 Oct 2008

Recommended
F1000 Factor 3.0

Confirmation
 Supraspinal glial-neuronal interactions contribute to descending pain facilitation.
Wei F, Guo W, …, Ren K, Dubner R
J Neurosci 2008 Oct 15 28(42):10482-95 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Barry Sessle with Pavel S Cherkas
Evaluated 30 Oct 2008

Recommended
F1000 Factor 3.0

Hypothesis
 Change of AMPA receptors in spinal nociceptive synapses during inflammatory hyperalgesia.
Wang W, Huang J
J Neurosci 2008 Oct 8 28(41):10185-6 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Allan Gottschalk
Evaluated 23 Oct 2008

Recommended
F1000 Factor 3.0

Hypothesis
 Quantitative sensory testing in the German Research Network on Neuropathic Pain (DFNS): standardized protocol and reference values.
Rolke R, Baron R, …, Valet M, Wasserka B
Pain 2006 Aug 123(3):231-43 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Henrik Kehlet with Eske Kvanner Aasvang
Evaluated 21 Oct 2008

Must Read
F1000 Factor 6.0

Confirmation
Controversial
 MF63 [2-(6-chloro-1H-phenanthro[9,10-d]imidazol-2-yl)-isophthalonitrile], a selective microsomal prostaglandin E synthase-1 inhibitor, relieves pyresis and pain in preclinical models of inflammation.
Xu D, Rowland SE, …, Audoly L, Riendeau D
J Pharmacol Exp Ther 2008 Sep 326(3):754-63 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Hanns Ulrich Zeilhofer with Ilja Broll
Evaluated 16 Oct 2008

Must Read
F1000 Factor 6.0

Controversial
 Intraoperative low-dose ketamine does not prevent a remifentanil-induced increase in morphine requirement after pediatric scoliosis surgery.
Engelhardt T, Zaarour C, …, Howard A, Crawford MW
Anesth Analg 2008 Oct 107(4):1170-5 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Francis Veyckemans
Evaluated 15 Oct 2008

Recommended
F1000 Factor 3.0

New Finding
 TRP channels and ASICs mediate mechanical hyperalgesia in models of inflammatory muscle pain and delayed onset muscle soreness.
Fujii Y, Ozaki N, …, Furukawa K, Sugiura Y
Pain 2008 Sep 30 [abstract on PubMed] [related articles] [full text]
Selected by | Paul Green
Evaluated 14 Oct 2008

Recommended
F1000 Factor 3.0

Hypothesis
New Finding
 General Anesthetics Sensitize the Capsaicin Receptor TRPV1.
Cornett P, Matta J, Ahern G
Mol Pharmacol 2008 Aug 8 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Robert Dickinson
Evaluated 8 Oct 2008


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