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Recommended
F1000 Factor 3.0

New Finding
Controversial
Aspirin and the in vitro linear relationship between thromboxane A2-mediated platelet aggregation and platelet production of thromboxane A2.
Armstrong PC, Truss NJ, …, Mitchell JA, Warner TD
J Thromb Haemost 2008 Nov 6(11):1933-43 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Wolfgang Korte
Evaluated 25 Nov 2008

Must Read
F1000 Factor 6.0

Hypothesis
Breast cancer and use of nonsteroidal anti-inflammatory drugs: a meta-analysis.
Takkouche B, Regueira-Méndez C, Etminan M
J Natl Cancer Inst 2008 Oct 15 100(20):1439-47 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Jeanine Genkinger with Anita Koushik
Evaluated 19 Nov 2008

Must Read
F1000 Factor 6.0

Hypothesis
Identification of a BK channel auxiliary protein controlling molecular and behavioral tolerance to alcohol.
Martin GE, Hendrickson LM, …, Tapper AR, Treistman SN
Proc Natl Acad Sci U S A 2008 Nov 11 105(45):17543-8 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Gregg Homanics with David Werner
Evaluated 19 Nov 2008

Recommended
F1000 Factor 3.2

Hypothesis
The effects of interrupted or continuous administration of sevoflurane on preconditioning before cardio-pulmonary bypass in coronary artery surgery: comparison with continuous propofol.
Bein B, Renner J, …, Fraund S, Scholz J
Anaesthesia 2008 Oct 63(10):1046-55 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Michael Irwin with Zhengyuan Xia / Stefan De Hert
First evaluation 14 Nov 2008 | Latest evaluation 27 Nov 2008

Recommended
F1000 Factor 3.0

New Finding
Alternative translation initiation in rat brain yields K2P2.1 potassium channels permeable to sodium.
Thomas D, Plant LD, …, McCrossan ZA, Goldstein SA
Neuron 2008 Jun 26 58(6):859-70 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Douglas Bayliss
Evaluated 12 Nov 2008

Recommended
F1000 Factor 3.0

Confirmation
Retrospective evaluation of a computerized physician order entry adaptation to prevent prescribing errors in a pediatric emergency department.
Sard BE, Walsh KE, …, Moschetti W, Bauchner H
Pediatrics 2008 Oct 122(4):782-7 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Alan Merry with Craig Webster
Evaluated 4 Nov 2008

Recommended
F1000 Factor 3.0

New Finding
Controversial
Postoperative pain and analgesic requirements after anesthesia with sevoflurane, desflurane or propofol.
Fassoulaki A, Melemeni A, …, Siafaka I, Sarantopoulos C
Anesth Analg 2008 Nov 107(5):1715-9 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Martin Angst
Evaluated 3 Nov 2008

Must Read
F1000 Factor 6.0

Confirmation
New Finding
Isoflurane modulates excitability in the mouse thalamus via GABA-dependent and GABA-independent mechanisms.
Ying SW, Werner DF, …, Harrison NL, Goldstein PA
Neuropharmacology 2008 Oct 9 [abstract on PubMed] [related articles] [full text]
Selected by | M Bruce MacIver
Evaluated 31 Oct 2008

Recommended
F1000 Factor 3.2

Confirmation
Hypothesis
Milrinone use is associated with postoperative atrial fibrillation after cardiac surgery.
Fleming GA, Murray KT, …, Brown NJ, Pretorius M
Circulation 2008 Oct 14 118(16):1619-25 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | John Augoustides / Stefan De Hert
First evaluation 31 Oct 2008 | Latest evaluation 26 Nov 2008

Must Read
F1000 Factor 4.8

New Finding
Spatial memory is intact in aged rats after propofol anesthesia.
Lee IH, Culley DJ, …, Tanzi RE, Crosby G
Anesth Analg 2008 Oct 107(4):1211-5 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Misha Perouansky / M Bruce MacIver
First evaluation 27 Oct 2008 | Latest evaluation 3 Nov 2008


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