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Recommended
F1000 Factor 3.0

New Finding
Can we really predict the change in serum sodium levels? An analysis of currently proposed formulae in hypernatraemic patients.
Lindner G, Schwarz C, …, Oberbauer R, Druml W
Nephrol Dial Transplant 2008 Nov 23(11):3501-8 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Saraladevi Naicker with Graham Paget
Evaluated 1 Dec 2008

Recommended
F1000 Factor 3.0

Confirmation
Acute, muscle-type specific insulin resistance following injury.
Thompson LH, Kim HT, …, Kokorina NA, Messina JL
Mol Med 2008 Nov-Dec 14(11-12):715-23 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Eric Nylen
Evaluated 27 Nov 2008

Must Read
F1000 Factor 6.0

Refutation
Intensive insulin therapy after severe traumatic brain injury: a randomized clinical trial.
Bilotta F, Caramia R, …, Santoro A, Rosa G
Neurocrit Care 2008 9(2):159-66 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Elfyn Thomas with Tod Guest
Evaluated 6 Nov 2008

Recommended
F1000 Factor 3.2

Confirmation
Hypothesis
Intensive care unit hypoglycemia predicts depression during early recovery from acute lung injury.
Dowdy DW, Dinglas V, …, Shanholtz C, Needham DM
Crit Care Med 2008 Oct 36(10):2726-33 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Sean Keenan / Jean-Charles Preiser
First evaluation 1 Oct 2008 | Latest evaluation 25 Nov 2008

Exceptional
F1000 Factor 8.0

Confirmation
New Finding
Tech Advance
Hepatocyte-specific ablation of Foxa2 alters bile acid homeostasis and results in endoplasmic reticulum stress.
Bochkis IM, Rubins NE, …, Friedman JR, Kaestner KH
Nat Med 2008 Aug 14(8):828-36 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Meenakshisundaram Ananthanarayanan / Marc Jeschke with Katsuhiro Kita
First evaluation 23 Sep 2008 | Latest evaluation 18 Nov 2008

Must Read
F1000 Factor 6.4
Articles that inform your practice or change your way of thinking Changes
Clinical Practice

Confirmation
New Finding
Benefits and risks of tight glucose control in critically ill adults: a meta-analysis.
Soylemez Wiener R, Wiener DC, Larson RJ
JAMA 2008 Aug 27 300(8):933-44 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Bruce Bistrian / Ian Herrick
First evaluation 11 Sep 2008 | Latest evaluation 24 Nov 2008

Recommended
F1000 Factor 3.0

Hypothesis
Alterations in glucose homeostasis in the pediatric intensive care unit: Hyperglycemia and glucose variability are associated with increased mortality and morbidity*
Hirshberg E, Larsen G, Van Duker H
Pediatr Crit Care Med 2008 May 19 [abstract on PubMed] [related articles] [full text]
Selected by | Brendan O'Hare with Filipa Miranda
Evaluated 4 Sep 2008

Exceptional
F1000 Factor 9.0

New Finding
Essential roles of PI(3)K-p110beta in cell growth, metabolism and tumorigenesis.
Jia S, Liu Z, …, Roberts TM, Zhao JJ
Nature 2008 Aug 7 454(7205):776-9 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Marc Jeschke
Evaluated 29 Aug 2008

Recommended
F1000 Factor 3.0

New Finding
Blood glucose concentration and outcome of critical illness: the impact of diabetes.
Egi M, Bellomo R, …, Hegarty C, Bailey M
Crit Care Med 2008 Aug 36(8):2249-55 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Jean-Charles Preiser
Evaluated 14 Aug 2008

Must Read
F1000 Factor 4.8
Articles that inform your practice or change your way of thinking Changes
Clinical Practice

Confirmation
New Finding
Inadequate blood glucose control is associated with in-hospital mortality and morbidity in diabetic and nondiabetic patients undergoing cardiac surgery.
Ascione R, Rogers CA, Rajakaruna C, Angelini GD
Circulation 2008 Jul 8 118(2):113-23 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Gregor Theilmeier with Jan Larmann / John Augoustides
First evaluation 7 Aug 2008 | Latest evaluation 17 Oct 2008


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