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Must Read
F1000 Factor 6.0

New Finding
Distinct hemodynamic patterns of septic shock at presentation to pediatric intensive care.
Brierley J, Peters MJ
Pediatrics 2008 Oct 122(4):752-9 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Francis Leclerc
Evaluated 26 Nov 2008

Recommended
F1000 Factor 3.0

Hypothesis
Dexmedetomidine: a novel drug for the treatment of atrial and junctional tachyarrhythmias during the perioperative period for congenital cardiac surgery: a preliminary study.
Chrysostomou C, Beerman L, …, Morell VO, Munoz R
Anesth Analg 2008 Nov 107(5):1514-22 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Victor Baum
Evaluated 31 Oct 2008

Recommended
F1000 Factor 3.0

Confirmation
Pre-existing disease is associated with a significantly higher risk of death in severe respiratory syncytial virus (RSV) infection.
Thorburn K
Arch Dis Child 2008 Jul 24 [abstract on PubMed] [related articles] [full text]
Selected by | Simon Nadel with Lee Cainer
Evaluated 13 Oct 2008

Must Read
F1000 Factor 6.0

Confirmation
Extubation in the operating room after Fontan's procedure: effect on practice and outcomes.
Morales DL, Carberry KE, …, Fraser CD, Diaz LK
Ann Thorac Surg 2008 Aug 86(2):576-81; discussion 581-2 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Victor Baum
Evaluated 2 Oct 2008

Must Read
F1000 Factor 6.0

Controversial
An emerging clinical paradigm: the cuffed pediatric endotracheal tube.
Aker J
AANA J 2008 Aug 76(4):293-300 [abstract on PubMed] [related articles] [order article]
Selected by | Samuel Ajizian
Evaluated 19 Sep 2008

Recommended
F1000 Factor 3.0

Controversial
Serum neutrophil gelatinase-associated lipocalin (NGAL) as a marker of acute kidney injury in critically ill children with septic shock.
Wheeler DS, Devarajan P, …, Cvijanovich N, Wong HR
Crit Care Med 2008 Apr 36(4):1297-303 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Michael Joannidis with Marianne Schmid
Evaluated 18 Sep 2008

Recommended
F1000 Factor 3.0

Hypothesis
Alterations in glucose homeostasis in the pediatric intensive care unit: Hyperglycemia and glucose variability are associated with increased mortality and morbidity*
Hirshberg E, Larsen G, Van Duker H
Pediatr Crit Care Med 2008 May 19 [abstract on PubMed] [related articles] [full text]
Selected by | Brendan O'Hare with Filipa Miranda
Evaluated 4 Sep 2008

Exceptional
F1000 Factor 9.0
Articles that inform your practice or change your way of thinking Changes
Clinical Practice

Confirmation
The effect of hematocrit during hypothermic cardiopulmonary bypass in infant heart surgery: results from the combined Boston hematocrit trials.
Wypij D, Jonas RA, …, Laussen PC, Newburger JW
J Thorac Cardiovasc Surg 2008 Feb 135(2):355-60 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | James Tweddell
Evaluated 2 Sep 2008

Exceptional
F1000 Factor 9.7

Confirmation
New Finding
Pyogenic bacterial infections in humans with MyD88 deficiency.
von Bernuth H, Picard C, …, Puel A, Casanova JL
Science 2008 Aug 1 321(5889):691-6 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | John Routes with James Verbsky / Shawn Skerrett / Philipp M Lepper
First evaluation 28 Aug 2008 | Latest evaluation 25 Sep 2008


Recommended
F1000 Factor 3.2

Hypothesis
New Finding
Anemia, blood loss, and blood transfusions in North American children in the intensive care unit.
Bateman ST, Lacroix J, …, Randolph AG, Pediatric Acute Lung Injury and Sepsis Investigators Network
Am J Respir Crit Care Med 2008 Jul 1 178(1):26-33 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Margaret Parker with Daniel Sloniewsky / Philippa Newfield
First evaluation 5 Aug 2008 | Latest evaluation 24 Sep 2008


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