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Recommended
F1000 Factor 3.0

New Finding
Genetic evidence of serum phosphate-independent functions of FGF-23 on bone.
Sitara D, Kim S, …, Erben RG, Lanske B
PLoS Genet 2008 4(8):e1000154 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Paolo Bianco with Mara Riminucci
Evaluated 28 Nov 2008

Recommended
F1000 Factor 3.0

New Finding
Sodium thiosulfate prevents vascular calcifications in uremic rats.
Pasch A, Schaffner T, …, Frey FJ, Farese S
Kidney Int 2008 Dec 74(11):1444-53 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Daniela Riccardi
Evaluated 28 Nov 2008

Recommended
F1000 Factor 3.0

New Finding
Granulocyte colony-stimulating factor induces osteoblast apoptosis and inhibits osteoblast differentiation.
Christopher MJ, Link DC
J Bone Miner Res 2008 Nov 23(11):1765-74 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Joseph Bidwell
Evaluated 26 Nov 2008

Recommended
F1000 Factor 3.0

New Finding
Klotho Ablation Converts the Biochemical and Skeletal Alterations in FGF23 (R176Q) Transgenic Mice to a Klotho Deficient Phenotype.
Bai X, Dinghong Q, …, Goltzman D, Karaplis AC
Am J Physiol Endocrinol Metab 2008 Nov 4 [abstract on PubMed] [related articles] [full text]
Selected by | Kenneth White
Evaluated 19 Nov 2008

Recommended
F1000 Factor 3.0

Tech Advance
GNAS defects identified by stimulatory G protein alpha subunit signalling studies in platelets.
Freson K, Izzi B, …, Jaeken J, Van Geet C
J Clin Endocrinol Metab 2008 Sep 23 [abstract on PubMed] [related articles] [full text]
Selected by | Caroline Silve
Evaluated 19 Nov 2008

Recommended
F1000 Factor 3.0

New Finding
Tech Advance
Comparison of the Effect of Denosumab and Alendronate on Bone Mineral Density and Biochemical Markers of Bone Turnover in Postmenopausal Women With Low Bone Mass: A Randomized, Blinded, Phase 3 Trial.
Brown JP, Prince RL, …, San Martin J, Bone HG
J Bone Miner Res 2008 Sep 3 [abstract on PubMed] [related articles] [full text]
Selected by | Peter Taylor with Sonya Abraham
Evaluated 17 Nov 2008

Recommended
F1000 Factor 3.0

Hypothesis
Heart failure is a risk factor for orthopedic fracture: a population-based analysis of 16,294 patients.
van Diepen S, Majumdar SR, …, McAlister FA, Ezekowitz JA
Circulation 2008 Nov 4 118(19):1946-52 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Jalal Ghali
Evaluated 6 Nov 2008

Must Read
F1000 Factor 6.0
Articles that inform your practice or change your way of thinking Changes
Clinical Practice

New Finding
The decline in hip bone density after gastric bypass surgery is associated with extent of weight loss.
Fleischer J, Stein EM, …, McMahon DJ, Silverberg SJ
J Clin Endocrinol Metab 2008 Oct 93(10):3735-40 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Peter Ebeling with Claudia Gagnon
Evaluated 5 Nov 2008

Recommended
F1000 Factor 3.0

Controversial
Estrogen-progestin contraceptive use during adolescence prevents bone mass acquisition: a 4-year follow-up study.
Pikkarainen E, Lehtonen-Veromaa M, …, Kautiainen H, Viikari J
Contraception 2008 Sep 78(3):226-31 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Richard Anderson
Evaluated 4 Nov 2008

Recommended
F1000 Factor 3.0

Hypothesis
Cortical and trabecular bone distribution in the femoral neck in osteoporosis and osteoarthritis.
Blain H, Chavassieux P, …, Maury P, Delmas PD
Bone 2008 Nov 43(5):862-8 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Thomas Link with Ahi Sema Issever
Evaluated 4 Nov 2008


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