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Browse > Gastroenterology & Hepatology > Inflammatory Bowel Disease
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Recommended
F1000 Factor 3.0

Controversial
 Predicting relapse in Crohn's disease: a biopsychosocial model.
Bitton A, Dobkin PL, …, Franchimont D, Wild GE
Gut 2008 Oct 57(10):1386-92 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Ingvar Bjarnason
Evaluated 28 Nov 2008

Must Read
F1000 Factor 6.0
Articles that inform your practice or change your way of thinking Changes
Clinical Practice

New Finding
 Therapy of metronidazole with azathioprine to prevent postoperative recurrence of Crohn's disease: a controlled randomized trial.
D'Haens GR, Vermeire S, …, Van Olmen G, Rutgeerts P
Gastroenterology 2008 Oct 135(4):1123-9 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Paul Pavli
Evaluated 24 Nov 2008

Recommended
F1000 Factor 3.0

New Finding
Tech Advance
 Once-daily versus three-times-daily mesalazine granules in active ulcerative colitis: A double-blind, double-dummy, randomised non-inferiority trial.
Kruis W, Kiudelis G, …, Greinwald R, Müller R
Gut 2008 Oct 2 [abstract on PubMed] [related articles] [full text]
Selected by | Russell Cohen
Evaluated 30 Oct 2008

Recommended
F1000 Factor 3.0

New Finding
 The role of the transcription factor AP-1 in colitis-associated and beta-catenin-dependent intestinal tumorigenesis in mice.
Hasselblatt P, Gresh L, …, Guinea-Viniegra J, Wagner EF
Oncogene 2008 Oct 23 27(47):6102-9 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Sharon DeMorrow
Evaluated 29 Oct 2008

Recommended
F1000 Factor 3.0
Articles that inform your practice or change your way of thinking Changes
Clinical Practice

New Finding
 Screening and surveillance colonoscopy in chronic Crohn's colitis: results of a surveillance program spanning 25 years.
Friedman S, Rubin PH, …, Harpaz N, Present DH
Clin Gastroenterol Hepatol 2008 Sep 6(9):993-8; quiz 953-4 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Maria Abreu with Paul A Feldman
Evaluated 27 Oct 2008

Recommended
F1000 Factor 3.0

Confirmation
 Decrease in the Numbers of Dendritic Cells and CD4+ T Cells in Cerebral Perivascular Spaces Due to Natalizumab.
Martin MD, Cravens PD, …, Kleinschmidt-Demasters BK, Stüve O
Arch Neurol 2008 Oct 13 [abstract on PubMed] [related articles] [full text]
Selected by | Timothy Vollmer
Evaluated 20 Oct 2008

Recommended
F1000 Factor 3.0

New Finding
 Loss of the autophagy protein Atg16L1 enhances endotoxin-induced IL-1 production
Saitoh T, Fujita N, …, Yoshimoro T, Akira S
Nature 2008
Selected by | Jack Satsangi with Charlie Lees
Evaluated 13 Oct 2008

Must Read
F1000 Factor 6.0

New Finding
 A key role for autophagy and the autophagy gene ATG16L1 in mouse and human intestinal Paneth cells
Caldwell K, Liu J, Stappenbeck T S, Virgin H W
Nature 2008
Selected by | Jack Satsangi with Charles Lees
Evaluated 10 Oct 2008

Recommended
F1000 Factor 3.0

New Finding
 Sequence variants in IL10, ARPC2 and multiple other loci contribute to ulcerative colitis susceptibility.
Franke A, Balschun T, …, Mathew CG, Schreiber S
Nat Genet 2008 Oct 5 [abstract on PubMed] [related articles] [full text]
Selected by | Jack Satsangi
Evaluated 9 Oct 2008

Must Read
F1000 Factor 6.4

Hypothesis
New Finding
 XBP1 links ER stress to intestinal inflammation and confers genetic risk for human inflammatory bowel disease.
Kaser A, Lee AH, …, Glimcher LH, Blumberg RS
Cell 2008 Sep 5 134(5):743-56 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Tor Savidge / Eduard Stange
First evaluation 7 Oct 2008 | Latest evaluation 12 Oct 2008



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