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Browse > Gastroenterology & Hepatology > Liver Biology & Pathobiology
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Must Read
F1000 Factor 6.0

New Finding
 Extrahepatic cholestasis increases liver stiffness (FibroScan) irrespective of fibrosis.
Millonig G, Reimann FM, …, Seitz HK, Mueller S
Hepatology 2008 Nov 48(5):1718-23 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Jonathan A Dranoff
Evaluated 26 Nov 2008

Exceptional
F1000 Factor 9.0

New Finding
 Gene expression in fixed tissues and outcome in hepatocellular carcinoma.
Hoshida Y, Villanueva A, …, Llovet JM, Golub TR
N Engl J Med 2008 Nov 6 359(19):1995-2004 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Didier Samuel
Evaluated 24 Nov 2008

Recommended
F1000 Factor 3.0

Confirmation
New Finding
 Hepatic AdipoR2 signaling plays a protective role against progression of nonalcoholic steatohepatitis in mice.
Tomita K, Oike Y, …, Ohkura T, Hibi T
Hepatology 2008 Aug 48(2):458-73 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Fabio Marra with Cristiana Bertolani
Evaluated 21 Nov 2008

Recommended
F1000 Factor 3.0

Confirmation
 Identification and characterization of metabolically benign obesity in humans.
Stefan N, Kantartzis K, …, Fritsche A, Häring HU
Arch Intern Med 2008 Aug 11 168(15):1609-16 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Caryl Nowson with Catherine Huggins
Evaluated 20 Nov 2008

Recommended
F1000 Factor 3.0

Confirmation
 RNA interference targeting the platelet-derived growth factor receptor beta subunit ameliorates experimental hepatic fibrosis in rats.
Chen SW, Zhang XR, …, Xie WF, Chen YX
Liver Int 2008 May 6 [abstract on PubMed] [related articles] [full text]
Selected by | Ralf Weiskirchen with Erawan Borkham-Kamphorst
Evaluated 19 Nov 2008

Recommended
F1000 Factor 3.0

New Finding
 The role of the transcription factor AP-1 in colitis-associated and beta-catenin-dependent intestinal tumorigenesis in mice.
Hasselblatt P, Gresh L, …, Guinea-Viniegra J, Wagner EF
Oncogene 2008 Oct 23 27(47):6102-9 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Sharon DeMorrow
Evaluated 29 Oct 2008

Exceptional
F1000 Factor 9.0

New Finding
 LXR signaling couples sterol metabolism to proliferation in the acquired immune response.
Bensinger SJ, Bradley MN, …, Jamieson BD, Tontonoz P
Cell 2008 Jul 11 134(1):97-111 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Percy Knolle
Evaluated 15 Oct 2008


Recommended
F1000 Factor 3.0

Confirmation
 FXR: a metabolic regulator and cell protector.
Wang YD, Chen WD, Moore DD, Huang W
Cell Res 2008 Sep 30 [abstract on PubMed] [related articles] [full text]
Selected by | Guorong Xu with Monica Saumoy
Evaluated 14 Oct 2008

Must Read
F1000 Factor 6.4

Confirmation
New Finding
 Hedgehog signaling regulates epithelial-mesenchymal transition during biliary fibrosis in rodents and humans.
Omenetti A, Porrello A, …, Schuppan D, Diehl AM
J Clin Invest 2008 Oct 1 118(10):3331-3342 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Frank Strutz / Frank Lammert with Susanne Weber
First evaluation 26 Sep 2008 | Latest evaluation 24 Oct 2008

Exceptional
F1000 Factor 8.0

Confirmation
New Finding
Tech Advance
 Hepatocyte-specific ablation of Foxa2 alters bile acid homeostasis and results in endoplasmic reticulum stress.
Bochkis IM, Rubins NE, …, Friedman JR, Kaestner KH
Nat Med 2008 Aug 14(8):828-36 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Meenakshisundaram Ananthanarayanan / Marc Jeschke with Katsuhiro Kita
First evaluation 23 Sep 2008 | Latest evaluation 18 Nov 2008


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