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Browse > Gastroenterology & Hepatology > Liver Failure & Liver Disease
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Must Read
F1000 Factor 6.0

New Finding
 Extrahepatic cholestasis increases liver stiffness (FibroScan) irrespective of fibrosis.
Millonig G, Reimann FM, …, Seitz HK, Mueller S
Hepatology 2008 Nov 48(5):1718-23 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Jonathan A Dranoff
Evaluated 26 Nov 2008

Exceptional
F1000 Factor 9.0

New Finding
 Gene expression in fixed tissues and outcome in hepatocellular carcinoma.
Hoshida Y, Villanueva A, …, Llovet JM, Golub TR
N Engl J Med 2008 Nov 6 359(19):1995-2004 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Didier Samuel
Evaluated 24 Nov 2008

Recommended
F1000 Factor 3.0

Confirmation
New Finding
 Hepatic AdipoR2 signaling plays a protective role against progression of nonalcoholic steatohepatitis in mice.
Tomita K, Oike Y, …, Ohkura T, Hibi T
Hepatology 2008 Aug 48(2):458-73 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Fabio Marra with Cristiana Bertolani
Evaluated 21 Nov 2008

Must Read
F1000 Factor 6.0

New Finding
 Genetic variation in PNPLA3 confers susceptibility to nonalcoholic fatty liver disease.
Romeo S, Kozlitina J, …, Cohen JC, Hobbs HH
Nat Genet 2008 Sep 25 [abstract on PubMed] [related articles] [full text]
Selected by | Tom Karlsen with Espen Melum
Evaluated 19 Nov 2008

Recommended
F1000 Factor 3.0

Confirmation
 RNA interference targeting the platelet-derived growth factor receptor beta subunit ameliorates experimental hepatic fibrosis in rats.
Chen SW, Zhang XR, …, Xie WF, Chen YX
Liver Int 2008 May 6 [abstract on PubMed] [related articles] [full text]
Selected by | Ralf Weiskirchen with Erawan Borkham-Kamphorst
Evaluated 19 Nov 2008

Must Read
F1000 Factor 6.0
Articles that inform your practice or change your way of thinking Changes
Clinical Practice

Tech Advance
 Chemotherapy for colorectal cancer liver metastases.
Alberts SR, Wagman LD
Oncologist 2008 Oct 13(10):1063-73 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Gilberto Schwartsmann with Fabio Leal
Evaluated 10 Nov 2008

Recommended
F1000 Factor 3.0

New Finding
 The role of the transcription factor AP-1 in colitis-associated and beta-catenin-dependent intestinal tumorigenesis in mice.
Hasselblatt P, Gresh L, …, Guinea-Viniegra J, Wagner EF
Oncogene 2008 Oct 23 27(47):6102-9 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Sharon DeMorrow
Evaluated 29 Oct 2008

Recommended
F1000 Factor 3.0

Controversial
 Retinol and alpha-Tocopherol in Morbid Obesity and Nonalcoholic Fatty Liver Disease.
Botella-Carretero JI, Balsa JA, …, Díaz-Enriquez M, Escobar-Morreale HF
Obes Surg 2008 Oct 2 [abstract on PubMed] [related articles] [full text]
Selected by | Zecharia Madar
Evaluated 28 Oct 2008

Recommended
F1000 Factor 3.0

Confirmation
 Angiogenesis in chronic liver disease.
Amarapurkar AD, Amarapurkar DN, Vibhav S, Patel ND
Ann Hepatol 2007 Jul-Sep 6(3):170-3 [abstract on PubMed] [related articles] [order article]
Selected by | Jayant Talwalkar
Evaluated 16 Oct 2008

Recommended
F1000 Factor 3.0

Confirmation
 FXR: a metabolic regulator and cell protector.
Wang YD, Chen WD, Moore DD, Huang W
Cell Res 2008 Sep 30 [abstract on PubMed] [related articles] [full text]
Selected by | Guorong Xu with Monica Saumoy
Evaluated 14 Oct 2008


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