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Recommended
F1000 Factor 3.0

New Finding
 A multicenter, randomized clinical trial comparing zoledronic acid versus observation in patients with asymptomatic myeloma.
Musto P, Petrucci MT, …, Palumbo A, GIMEMA (Italian Group for Adult Hematologic Diseases)/Multiple Myeloma Working Party and the Italian Myeloma Network
Cancer 2008 Oct 1 113(7):1588-95 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Xavier Leleu with J Gay
Evaluated 15 Oct 2008

Recommended
F1000 Factor 3.0
Articles that inform your practice or change your way of thinking Changes
Clinical Practice

Hypothesis
New Finding
Controversial
 Survival after T cell-depleted haploidentical stem cell transplantation is improved using the mother as donor.
Stern M, Ruggeri L, …, Aversa F, Velardi A
Blood 2008 Oct 1 112(7):2990-5 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Ginna Laport
Evaluated 14 Oct 2008

Recommended
F1000 Factor 3.0

Confirmation
 The effect of a quantitative resuscitation strategy on mortality in patients with sepsis: a meta-analysis.
Jones AE, Brown MD, …, Kline JA, Emergency Medicine Shock Research Network investigators
Crit Care Med 2008 Oct 36(10):2734-9 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Thomas Luecke
Evaluated 14 Oct 2008

Recommended
F1000 Factor 3.0

Confirmation
 The differences between venous air embolism and fat embolism in routine intraoperative monitoring methods, transesophageal echocardiography, and fatal volume in pigs.
Wang AZ, Zhou M, Jiang W, Zhang WX
J Trauma 2008 Aug 65(2):416-23 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Naoto Morimura
Evaluated 14 Oct 2008

Recommended
F1000 Factor 3.0

New Finding
 Generation of pluripotent stem cells from adult human testis.
Conrad S, Renninger M, …, Stenzl A, Skutella T
Nature 2008 Oct 8 [abstract on PubMed] [related articles] [full text]
Selected by | Takashi Minegishi
Evaluated 14 Oct 2008

Must Read
F1000 Factor 4.8

Confirmation
Hypothesis
 Preneoplastic lesion growth driven by the death of adjacent normal stem cells.
Chao DL, Eck JT, …, Maley CC, Luebeck EG
Proc Natl Acad Sci U S A 2008 Sep 30 105(39):15034-9 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Martin Leverkus / Jean Marie Houghton
First evaluation 13 Oct 2008 | Latest evaluation 14 Oct 2008

Must Read
F1000 Factor 6.0
Articles that inform your practice or change your way of thinking Changes
Clinical Practice

Confirmation
 Management of Philadelphia negative chronic myeloproliferative disorders in pregnancy.
Griesshammer M, Struve S, Barbui T
Blood Rev 2008 Sep 22(5):235-45 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Bernard Wittels
Evaluated 8 Oct 2008

Recommended
F1000 Factor 3.0

Confirmation
Hypothesis
 In vivo reprogramming of adult pancreatic exocrine cells to beta-cells.
Zhou Q, Brown J, …, Rajagopal J, Melton DA
Nature 2008 Oct 2 455(7213):627-32 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Nelson Chao
Evaluated 8 Oct 2008


Recommended
F1000 Factor 3.0

Confirmation
 Bone marrow endothelial progenitors are defective in systemic sclerosis.
Del Papa N, Quirici N, …, Cortelezzi A, Lambertenghi-Deliliers G
Arthritis Rheum 2006 Aug 54(8):2605-15 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Jörg Distler with Christian Beyer
Evaluated 8 Oct 2008

Recommended
F1000 Factor 3.0

Hypothesis
 Abnormalities in the myeloid progenitor compartment in Down syndrome fetal liver precede acquisition of GATA1 mutations.
Tunstall-Pedoe O, Roy A, …, Vyas P, Roberts I
Blood 2008 Aug 8 [abstract on PubMed] [related articles] [full text]
Selected by | Christian Kratz
Evaluated 7 Oct 2008


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