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F1000 Factor 3.0
Articles that inform your practice or change your way of thinking Changes
Clinical Practice

Confirmation
 Novel exon 12 mutations in the HIF2A gene associated with erythrocytosis.
Percy MJ, Beer PA, …, McMullin MF, Lee FS
Blood 2008 Jun 1 111(11):5400-2 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Suzanne Watt
Evaluated 18 Jul 2008

Recommended
F1000 Factor 3.0

New Finding
 High risk of neutropenia in HIV-infected children following treatment with artesunate plus amodiaquine for uncomplicated malaria in Uganda.
Gasasira AF, Kamya MR, …, Havlir D, Dorsey G
Clin Infect Dis 2008 Apr 1 46(7):985-91 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Ric Price with Krispin Hajkowicz
Evaluated 17 Jul 2008

Recommended
F1000 Factor 3.0

New Finding
 Microvesicles in haemoglobinopathies offer insights into mechanisms of hypercoagulability, haemolysis and the effects of therapy.
Westerman M, Pizzey A, …, Mackie I, Porter J
Br J Haematol 2008 Jul 142(1):126-35 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Hans U Lutz
Evaluated 11 Jul 2008

Exceptional
F1000 Factor 9.0

New Finding
 A role of phosphatidylserine externalization in clearance of erythrocytes exposed to stress but not in eliminating aging populations of erythrocyte in mice.
Khandelwal S, Saxena RK
Exp Gerontol 2008 May 11 [abstract on PubMed] [related articles] [full text]
Selected by | Hans U Lutz
Evaluated 30 Jun 2008

Exceptional
F1000 Factor 9.0

New Finding
 Modulation of bone morphogenetic protein signaling in vivo regulates systemic iron balance.
Babitt JL, Huang FW, …, Andrews NC, Lin HY
J Clin Invest 2007 Jul 117(7):1933-9 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Jonathan Barasch
Evaluated 13 Jun 2008

Recommended
F1000 Factor 3.0

Hypothesis
New Finding
 Lack of Duffy antigen expression is associated with organ damage in patients with sickle cell disease.
Afenyi-Annan A, Kail M, …, Ashley-Koch A, Telen MJ
Transfusion 2008 May 48(5):917-24 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | George Garratty
Evaluated 11 Jun 2008

Exceptional
F1000 Factor 9.0

Hypothesis
New Finding
 Mutations in EKLF/KLF1 form the molecular basis of the rare blood group In(Lu) phenotype.
Singleton BK, Burton NM, …, Brady RL, Anstee DJ
Blood 2008 May 16 [abstract on PubMed] [related articles] [full text]
Selected by | Marilyn Telen
Evaluated 6 Jun 2008

Recommended
F1000 Factor 3.0

Hypothesis
New Finding
 AML1 mutations induced MDS and MDS/AML in a mouse BMT model.
Watanabe-Okochi N, Kitaura J, …, Inaba T, Kitamura T
Blood 2008 Apr 15 111(8):4297-308 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Elaine Sloand
Evaluated 5 Jun 2008

Recommended
F1000 Factor 3.0

Hypothesis
New Finding
 Regulation of iron homeostasis by the hypoxia-inducible transcription factors (HIFs).
Peyssonnaux C, Zinkernagel AS, …, Nizet V, Johnson RS
J Clin Invest 2007 Jul 117(7):1926-32 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Philipp M Lepper
Evaluated 3 Jun 2008

Must Read
F1000 Factor 6.0

Hypothesis
New Finding
 The serine protease TMPRSS6 is required to sense iron deficiency.
Du X, She E, …, Beutler E, Beutler B
Science 2008 May 23 320(5879):1088-92 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Philipp M Lepper
Evaluated 30 May 2008



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