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Recommended
F1000 Factor 3.0

Hypothesis
 Abnormalities in the myeloid progenitor compartment in Down syndrome fetal liver precede acquisition of GATA1 mutations.
Tunstall-Pedoe O, Roy A, …, Vyas P, Roberts I
Blood 2008 Aug 8 [abstract on PubMed] [related articles] [full text]
Selected by | Christian Kratz
Evaluated 7 Oct 2008

Must Read
F1000 Factor 6.0

Hypothesis
 Anti-CD38 antibody-mediated clearance of human repopulating cells masks the heterogeneity of leukemia-initiating cells.
Taussig DC, Miraki-Moud F, …, Gribben JG, Bonnet D
Blood 2008 Aug 1 112(3):568-75 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Zhu Chen
Evaluated 25 Sep 2008

Recommended
F1000 Factor 3.0

Confirmation
 Effect of transfusional iron intake on response to chelation therapy in beta-thalassemia major.
Cohen AR, Glimm E, Porter JB
Blood 2008 Jan 15 111(2):583-7 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Silverio Perrotta with Domenico Roberti
Evaluated 10 Sep 2008

Recommended
F1000 Factor 3.0

New Finding
 The incidence and implications of anti-heparin-platelet factor 4 antibody formation in a pediatric cardiac surgical population.
Mullen MP, Wessel DL, …, McGowan FX, Dinardo JA
Anesth Analg 2008 Aug 107(2):371-8 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Emad Mossad
Evaluated 22 Aug 2008

Must Read
F1000 Factor 6.4
Articles that inform your practice or change your way of thinking Changes
Clinical Practice

Confirmation
New Finding
Tech Advance
 Mutations and treatment outcome in cytogenetically normal acute myeloid leukemia.
Schlenk RF, Döhner K, …, Döhner H, German-Austrian Acute Myeloid Leukemia Study Group
N Engl J Med 2008 May 1 358(18):1909-18 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Effie Petersdorf / Richard Larson with Olatoyosi M Odenike
First evaluation 20 Aug 2008 | Latest evaluation 26 Sep 2008

Exceptional
F1000 Factor 9.0

Tech Advance
 TINF2, a component of the shelterin telomere protection complex, is mutated in dyskeratosis congenita.
Savage SA, Giri N, …, Lansdorp PM, Alter BP
Am J Hum Genet 2008 Feb 82(2):501-9 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Christian Kratz
Evaluated 1 Aug 2008


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F1000 Factor 3.0

New Finding
 High risk of neutropenia in HIV-infected children following treatment with artesunate plus amodiaquine for uncomplicated malaria in Uganda.
Gasasira AF, Kamya MR, …, Havlir D, Dorsey G
Clin Infect Dis 2008 Apr 1 46(7):985-91 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Ric Price with Krispin Hajkowicz
Evaluated 17 Jul 2008

Recommended
F1000 Factor 3.0

New Finding
 Microvesicles in haemoglobinopathies offer insights into mechanisms of hypercoagulability, haemolysis and the effects of therapy.
Westerman M, Pizzey A, …, Mackie I, Porter J
Br J Haematol 2008 Jul 142(1):126-35 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Hans U Lutz
Evaluated 11 Jul 2008

Recommended
F1000 Factor 3.0

New Finding
 Long-term follow-up of children who underwent hematopoeitic cell transplant (HCT) for AML or ALL at less than 3 years of age.
Perkins JL, Kunin-Batson AS, …, Anderson FS, Baker KS
Pediatr Blood Cancer 2007 Dec 49(7):958-63 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Bruce Camitta with Julie Talano
Evaluated 1 Jul 2008

Recommended
F1000 Factor 3.0

Tech Advance
 Fatal congenital thrombotic thrombocytopenic purpura with apparent ADAMTS13 inhibitor: in vitro inhibition of ADAMTS13 activity by hemoglobin.
Studt JD, Hovinga JA, …, Scheiflinger F, Lämmle B
Blood 2005 Jan 15 105(2):542-4 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Suresh Shelat
Evaluated 21 May 2008


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