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Must Read
F1000 Factor 6.0

New Finding
Tech Advance
 Extensive hematopoietic stem cell generation in the AGM region via maturation of VE-cadherin+CD45+ pre-definitive HSCs.
Taoudi S, Gonneau C, …, Taylor E, Medvinsky A
Cell Stem Cell 2008 Jul 3 3(1):99-108 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Marella De Bruijn with Gemma Swiers
Evaluated 14 Nov 2008

Recommended
F1000 Factor 3.0

Hypothesis
New Finding
Controversial
 Detection and characterization of CD133+ cancer stem cells in human solid tumours.
Tirino V, Desiderio V, …, De Rosa A, Papaccio G
PLoS ONE 2008 3(10):e3469 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Stephen Lessnick
Evaluated 3 Nov 2008

Recommended
F1000 Factor 3.0

Hypothesis
 A developmental model of sarcomagenesis defines a differentiation-based classification for liposarcomas.
Matushansky I, Hernando E, …, Cordon-Cardo C, Maki RG
Am J Pathol 2008 Apr 172(4):1069-80 [abstract on PubMed] [related articles] [FREE full text]
Selected by | William Tap
Evaluated 28 Oct 2008

Recommended
F1000 Factor 3.0

Hypothesis
 Defining Stem and Progenitor Cells within Adipose Tissue.
Lin G, Garcia M, …, Lue TF, Lin CS
Stem Cells Dev 2008 Jul 2 [abstract on PubMed] [related articles] [full text]
Selected by | Dietmar Werner Hutmacher with Maria Woodruff
Evaluated 27 Oct 2008

Exceptional
F1000 Factor 9.0

New Finding
Tech Advance
 Murine mesenchymal stem cells exhibit a restricted repertoire of functional chemokine receptors: comparison with human.
Chamberlain G, Wright K, …, Ashton B, Middleton J
PLoS ONE 2008 3(8):e2934 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Jan-Thorsten Schantz with Harvey Chim
Evaluated 22 Oct 2008

Recommended
F1000 Factor 3.0

Tech Advance
 Disease-specific induced pluripotent stem cells.
Park IH, Arora N, …, Hochedlinger K, Daley GQ
Cell 2008 Sep 5 134(5):877-86 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Paul Sanberg with David J Eve
Evaluated 17 Oct 2008


Exceptional
F1000 Factor 9.0

New Finding
 Induction of pluripotent stem cells from primary human fibroblasts with only Oct4 and Sox2.
Huangfu D, Osafune K, …, Muhlestein W, Melton DA
Nat Biotechnol 2008 Oct 12 [abstract on PubMed] [related articles] [full text]
Selected by | Jozef Lazar with Aron Guerts
Evaluated 17 Oct 2008

Recommended
F1000 Factor 3.0

New Finding
 Generation of pluripotent stem cells from adult human testis.
Conrad S, Renninger M, …, Stenzl A, Skutella T
Nature 2008 Oct 8 [abstract on PubMed] [related articles] [full text]
Selected by | Takashi Minegishi
Evaluated 14 Oct 2008


Must Read
F1000 Factor 4.8

Confirmation
Hypothesis
 Preneoplastic lesion growth driven by the death of adjacent normal stem cells.
Chao DL, Eck JT, …, Maley CC, Luebeck EG
Proc Natl Acad Sci U S A 2008 Sep 30 105(39):15034-9 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Martin Leverkus / Jean Marie Houghton
First evaluation 13 Oct 2008 | Latest evaluation 14 Oct 2008

Recommended
F1000 Factor 3.0

Confirmation
Hypothesis
 In vivo reprogramming of adult pancreatic exocrine cells to beta-cells.
Zhou Q, Brown J, …, Rajagopal J, Melton DA
Nature 2008 Oct 2 455(7213):627-32 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Nelson Chao
Evaluated 8 Oct 2008



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