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2-Dec-2008

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Browse > Infectious Diseases > HIV Infection & AIDS: Basic Science
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	Recommended
F1000 Factor 3.0

New Finding

Tech Advance

CTA1-DD adjuvant promotes strong immunity against human immunodeficiency virus type 1 envelope glycoproteins following mucosal immunization.
Sundling C, Schön K, …, Karlsson Hedestam GB, Lycke NY
J Gen Virol 2008 Dec 89(Pt 12):2954-64 [abstract on PubMed] [related articles] [full text] [order article]

Selected by | Luigi Buonaguro

Evaluated 1 Dec 2008

Exceptional

F1000 Factor 9.0

Changes
Clinical Practice

Hypothesis

Early Antiretroviral Therapy and Mortality among HIV-Infected Infants.
Violari A, Cotton MF, …, McIntyre JA, the CHER Study Team
N Engl J Med 2008 Nov 20 359(21):2233-2244 [abstract on PubMed] [related articles] [full text] [order article]

Selected by | Kayvon Modjarrad with Sana Dastgheyb

Evaluated 27 Nov 2008

	Must Read
F1000 Factor 6.0

Confirmation

Genome-scale RNAi screen for host factors required for HIV replication.
Zhou H, Xu M, …, Hazuda DJ, Espeseth AS
Cell Host Microbe 2008 Nov 13 4(5):495-504 [abstract on PubMed] [related articles] [full text] [order article]

Selected by | Hanneke Schuitemaker with Angélique van ‘t Wout
Evaluated 19 Nov 2008

	Must Read
F1000 Factor 4.8

Confirmation

New Finding

Activation of a dendritic cell-T cell axis by Ad5 immune complexes creates an improved environment for replication of HIV in T cells.
Perreau M, Pantaleo G, Kremer EJ
J Exp Med 2008 Nov 3 [abstract on PubMed] [related articles] [full text]

Selected by | Scott Sieg with Nicholas Funderburg / Paul Goepfert
First evaluation 13 Nov 2008 | Latest evaluation 18 Nov 2008

	Recommended
F1000 Factor 3.0

New Finding

Analysis of nevirapine (NVP) resistance in Ugandan infants who were HIV infected despite receiving single-Dose (SD) NVP versus SD NVP plus daily NVP up to 6 weeks of age to prevent HIV vertical transmission.
Church JD, Omer SB, …, Jackson JB, Eshleman SH
J Infect Dis 2008 Oct 1 198(7):1075-82 [abstract on PubMed] [related articles] [full text] [order article]

Selected by | Heather Jaspan
Evaluated 11 Nov 2008

	Must Read
F1000 Factor 6.0

Confirmation

Hypothesis

Direct evidence of extensive diversity of HIV-1 in Kinshasa by 1960.
Worobey M, Gemmel M, …, Gilbert MT, Wolinsky SM
Nature 2008 Oct 2 455(7213):661-4 [abstract on PubMed] [related articles] [full text] [order article]

Selected by | Matthew Dolan
Evaluated 6 Nov 2008

	Recommended
F1000 Factor 3.0

Confirmation

New Finding

B7-H1 up-regulation impairs myeloid DC and correlates with disease progression in chronic HIV-1 infection
Wang X, Zhang Z, …, Wu H, Wang FS
European Journal of Immunology 2008 38:1-11 [full text]

Selected by | Gabriella Scarlatti with Mariangela Cavarelli
Evaluated 6 Nov 2008

	Recommended
F1000 Factor 3.0

Confirmation

Hypothesis

New Finding

Global analysis of host-pathogen interactions that regulate early-stage HIV-1 replication.
König R, Zhou Y, …, Young JA, Chanda SK
Cell 2008 Oct 3 135(1):49-60 [abstract on PubMed] [related articles] [full text] [order article]

Selected by | Ariberto Fassati with Elena Sokolskaja
Evaluated 30 Oct 2008

	Recommended
F1000 Factor 3.0

New Finding

Development of regulatory T cells requires IL-7Ralpha stimulation by IL-7 or TSLP.
Mazzucchelli R, Hixon JA, …, Leonard WJ, Durum SK
Blood 2008 Oct 15 112(8):3283-92 [abstract on PubMed] [related articles] [full text] [order article]

Selected by | Javier Chinen with Usa Tantibhaedhyangkul
Evaluated 28 Oct 2008

	Recommended
F1000 Factor 3.0

Controversial

No major differences in the functional profile of HIV Gag and Nef-specific CD8+ responses between long-term nonprogressors and typical progressors.
López M, Soriano V, …, González-Lahoz J, Benito JM
AIDS Res Hum Retroviruses 2008 Sep 24(9):1185-95 [abstract on PubMed] [related articles] [full text] [order article]

Selected by | Holden Maecker
Evaluated 24 Oct 2008

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