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Must Read
F1000 Factor 6.0

Hypothesis
Functional and chronic anorectal and pelvic pain disorders.
Bharucha AE, Trabuco E
Gastroenterol Clin North Am 2008 Sep 37(3):685-96 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Philip Hanno
Evaluated 6 Oct 2008

Recommended
F1000 Factor 3.0

Hypothesis
Dose-response curve slope sets class-specific limits on inhibitory potential of anti-HIV drugs.
Shen L, Peterson S, …, Acosta EP, Siliciano RF
Nat Med 2008 Jul 14(7):762-6 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Jason Brenchley
Evaluated 6 Oct 2008


Must Read
F1000 Factor 6.0

Confirmation
New Finding
Mutations in STAT3 and IL12RB1 impair the development of human IL-17-producing T cells.
de Beaucoudrey L, Puel A, …, Picard C, Casanova JL
J Exp Med 2008 Jul 7 205(7):1543-50 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Lars Rogge
Evaluated 3 Oct 2008

Recommended
F1000 Factor 3.0

Confirmation
Emergence and Persistence of CXCR4-Tropic HIV-1 in a Population of Men from the Multicenter AIDS Cohort Study.
Shepherd JC, Jacobson LP, …, Quinn TC, Margolick JB
J Infect Dis 2008 Oct 15 198(8):1104-1112 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Eric Daar
Evaluated 3 Oct 2008

Must Read
F1000 Factor 6.0

Confirmation
Tech Advance
Controversial
Prevention of SIV rectal transmission and priming of T cell responses in macaques after local pre-exposure application of tenofovir gel.
Cranage M, Sharpe S, …, McGowan I, Shattock R
PLoS Med 2008 Aug 5 5(8):e157; discussion e157 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Marta Marthas
Evaluated 3 Oct 2008

Recommended
F1000 Factor 3.0

Confirmation
Use of B-type natriuretic peptide in the risk stratification of community-acquired pneumonia.
Christ-Crain M, Breidthardt T, …, Mueller B, Mueller C
J Intern Med 2008 Aug 264(2):166-76 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Charles Feldman with Erica Shaddock
Evaluated 3 Oct 2008

Must Read
F1000 Factor 6.0

New Finding
Tech Advance
Small-molecule inhibition of HIV-1 Vif.
Nathans R, Cao H, …, Stevenson M, Rana TM
Nat Biotechnol 2008 Sep 21 [abstract on PubMed] [related articles] [full text]
Selected by | Jason Barbour
Evaluated 2 Oct 2008

Recommended
F1000 Factor 3.0

Confirmation
Aspergillus fumigatus-induced IL-8 synthesis by respiratory epithelial cells is controlled by the PI3 kinase, p38 MAPK and ERK1/2 pathways and not by the TLR-MYD88 pathway.
Balloy V, Sallenave JM, …, Si-Tahar M, Chignard M
J Biol Chem 2008 Aug 14 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Cornelia Lass-Floerl with Susanne Perkhofer
Evaluated 2 Oct 2008

Must Read
F1000 Factor 6.0

Confirmation
Immune responses to human papillomavirus.
Stanley M
Vaccine 2006 Mar 30 24 Suppl 1:S16-22 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Paul Summers
Evaluated 1 Oct 2008

Recommended
F1000 Factor 3.0

New Finding
XIAP regulates cytosol-specific innate immunity to Listeria infection.
Bauler LD, Duckett CS, O'Riordan MX
PLoS Pathog 2008 Aug 4(8):e1000142 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Paul Klenerman
Evaluated 1 Oct 2008


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