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F1000 Factor 3.0

New Finding
Myelomonocytic cell recruitment causes fatal CNS vascular injury during acute viral meningitis.
Kim JV, Kang SS, Dustin ML, McGavern DB
Nature 2008 Nov 16 [abstract on PubMed] [related articles] [full text]
Selected by | Thomas Hawn
Evaluated 27 Nov 2008

Must Read
F1000 Factor 6.0

New Finding
Recent and rapid emergence of W-Beijing strains of Mycobacterium tuberculosis in Cape Town, South Africa.
Cowley D, Govender D, …, Wilkinson RJ, Nicol MP
Clin Infect Dis 2008 Nov 15 47(10):1252-9 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Guy Thwaites
Evaluated 25 Nov 2008

Recommended
F1000 Factor 3.0
Articles that inform your practice or change your way of thinking Changes
Clinical Practice

Confirmation
Tech Advance
A reliable diagnosis of human rabies based on analysis of skin biopsy specimens.
Dacheux L, Reynes JM, …, Sadorge C, Bourhy H
Clin Infect Dis 2008 Dec 1 47(11):1410-7 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Mary Warrell
Evaluated 21 Nov 2008

Recommended
F1000 Factor 3.0

Hypothesis
New Finding
Refutation
Western Equine Encephalitis submergence: lack of evidence for a decline in virus virulence.
Forrester NL, Kenney JL, …, Wang E, Weaver SC
Virology 2008 Oct 25 380(2):170-2 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Lyle Petersen with Jim Sejvar
Evaluated 17 Nov 2008

Recommended
F1000 Factor 3.0

New Finding
Aquaporin-4-binding autoantibodies in patients with neuromyelitis optica impair glutamate transport by down-regulating EAAT2.
Hinson SR, Roemer SF, …, Pittock SJ, Lennon VA
J Exp Med 2008 Oct 27 205(11):2473-81 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Charlotte Teunissen
Evaluated 6 Nov 2008

Recommended
F1000 Factor 3.0

New Finding
Role of selection in the emergence of lineages and the evolution of virulence in Neisseria meningitidis.
Buckee CO, Jolley KA, …, Gupta S, Maiden MC
Proc Natl Acad Sci U S A 2008 Sep 30 105(39):15082-7 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Edward Feil
Evaluated 28 Oct 2008

Recommended
F1000 Factor 3.0

New Finding
Suppression of transcription factor early growth response 1 reduces herpes simplex virus lethality in mice.
Chen SH, Yao HW, …, Li C, Chen SH
J Clin Invest 2008 Oct 1 118(10):3470-3477 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Mark Nicol with Ana Milovic
Evaluated 24 Oct 2008

Recommended
F1000 Factor 3.0

Confirmation
Decrease in the Numbers of Dendritic Cells and CD4+ T Cells in Cerebral Perivascular Spaces Due to Natalizumab.
Martin MD, Cravens PD, …, Kleinschmidt-Demasters BK, Stüve O
Arch Neurol 2008 Oct 13 [abstract on PubMed] [related articles] [full text]
Selected by | Timothy Vollmer
Evaluated 20 Oct 2008

Must Read
F1000 Factor 6.0

Hypothesis
New Finding
Controversial
TLR3 deficiency in patients with herpes simplex encephalitis.
Zhang SY, Jouanguy E, …, Abel L, Casanova JL
Science 2007 Sep 14 317(5844):1522-7 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Tom Solomon
Evaluated 17 Oct 2008

Must Read
F1000 Factor 6.0

New Finding
Controversial
Transient FTY720 treatment promotes immune-mediated clearance of a chronic viral infection.
Premenko-Lanier M, Moseley NB, …, Romagnoli PA, Altman JD
Nature 2008 Aug 14 454(7206):894-8 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Percy Knolle
Evaluated 15 Oct 2008



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