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F1000 Factor 3.0

New Finding
 "ROS-generating mitochondrial DNA mutations can regulate tumor cell metastasis"-a critical commentary.
Zielonka J, Kalyanaraman B
Free Radic Biol Med 2008 Aug 23 [abstract on PubMed] [related articles] [full text]
Selected by | Mark Berneburg
Evaluated 12 Oct 2008

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F1000 Factor 3.0

New Finding
 Induction chemotherapy and concurrent chemoradiotherapy for locoregionally advanced head and neck cancer: a multi-institutional phase II trial investigating three radiotherapy dose levels.
Salama JK, Stenson KM, …, Haraf DJ, Vokes EE
Ann Oncol 2008 Oct 19(10):1787-94 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Ricardo Hitt
Evaluated 10 Oct 2008

Must Read
F1000 Factor 6.0

New Finding
 Association of radiographic emphysema and airflow obstruction with lung cancer.
Wilson DO, Weissfeld JL, …, Shapiro SD, Sciurba FC
Am J Respir Crit Care Med 2008 Oct 1 178(7):738-44 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Patrick Nana-Sinkam with Shiva Rahmanian
Evaluated 10 Oct 2008

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F1000 Factor 3.0

New Finding
Tech Advance
 Genetically defined EWS/FLI1 model system suggests mesenchymal origin of Ewing's family tumors.
Potikyan G, France KA, …, Nelson SF, Denny CT
Lab Invest 2008 Oct 6 [abstract on PubMed] [related articles] [full text]
Selected by | Stephen Lessnick
Evaluated 10 Oct 2008

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F1000 Factor 6.0

Hypothesis
New Finding
 Induced ncRNAs allosterically modify RNA-binding proteins in cis to inhibit transcription.
Wang X, Arai S, …, Glass CK, Kurokawa R
Nature 2008 Jul 3 454(7200):126-30 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Stephen Lessnick
Evaluated 10 Oct 2008


Recommended
F1000 Factor 3.0

Confirmation
 Results of the EICESS-92 Study: two randomized trials of Ewing's sarcoma treatment--cyclophosphamide compared with ifosfamide in standard-risk patients and assessment of benefit of etoposide added to standard treatment in high-risk patients.
Paulussen M, Craft AW, …, Jürgens H, European Intergroup Cooperative Ewing's Sarcoma Study-92
J Clin Oncol 2008 Sep 20 26(27):4385-93 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Stephen Lessnick
Evaluated 10 Oct 2008

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F1000 Factor 3.0

Hypothesis
New Finding
 BMI-1 promotes ewing sarcoma tumorigenicity independent of CDKN2A repression.
Douglas D, Hsu JH, …, Triche TJ, Lawlor ER
Cancer Res 2008 Aug 15 68(16):6507-15 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Stephen Lessnick
Evaluated 10 Oct 2008

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F1000 Factor 3.0

New Finding
 Influence of HIV-related immunodeficiency on the risk of hepatocellular carcinoma.
Clifford GM, Rickenbach M, …, Franceschi S, Swiss HIV Cohort
AIDS 2008 Oct 18 22(16):2135-41 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | James Goedert
Evaluated 10 Oct 2008

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F1000 Factor 3.0

Hypothesis
 Lung Cancer Occurrence in Never-Smokers: An Analysis of 13 Cohorts and 22 Cancer Registry Studies.
Thun MJ, Hannan LM, …, Wilkens LR, Samet JM
PLoS Med 2008 Sep 9 5(9):e185 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Ellen Chang
Evaluated 9 Oct 2008

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F1000 Factor 6.0

Confirmation
New Finding
 Massage therapy versus simple touch to improve pain and mood in patients with advanced cancer: a randomized trial.
Kutner JS, Smith MC, …, Bryant LL, Fairclough DL
Ann Intern Med 2008 Sep 16 149(6):369-79 [abstract on PubMed] [related articles] [order article]
Selected by | Marcin Chwistek
Evaluated 9 Oct 2008


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