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Recommended
F1000 Factor
3.0
New Finding
The autophagy-related protein beclin 1 shows reduced expression in early Alzheimer disease and regulates amyloid beta accumulation in mice.
Pickford F, Masliah E, …, Levine B, Wyss-Coray T
J Clin Invest
2008 Jun
118
(6):2190-9 [
abstract on PubMed
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FREE full text
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Selected by
| Elio Scarpini with Daniela Galimberti
Evaluated 3 Sep 2008
Recommended
F1000 Factor
3.0
New Finding
Tech Advance
Selective changes of resting-state networks in individuals at risk for Alzheimer's disease.
Sorg C, Riedl V, …, Zimmer C, Wohlschläger AM
Proc Natl Acad Sci U S A
2007 Nov 20
104
(47):18760-5 [
abstract on PubMed
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Selected by
| Richard Levy with Emmanuelle Volle
Evaluated 2 Sep 2008
Recommended
F1000 Factor
3.0
Confirmation
Controversial
Refutation
Long-term effects of Abeta42 immunisation in Alzheimer's disease: follow-up of a randomised, placebo-controlled phase I trial.
Holmes C, Boche D, …, Zotova E, Nicoll JA
Lancet
2008 Jul 19
372
(9634):216-23 [
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Selected by
| Mark A. Smith
Evaluated 1 Sep 2008
Recommended
F1000 Factor
3.0
Confirmation
Tech Advance
Determination of catechins and catechin gallates in tissues by liquid chromatography with coulometric array detection and selective solid phase extraction.
Chu KO, Wang CC, …, Choy KW, Pang CP
J Chromatogr B Analyt Technol Biomed Life Sci
2004 Oct 25
810
(2):187-95 [
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Selected by
| Stephane Bastianetto
Evaluated 1 Sep 2008
Must Read
F1000 Factor
6.0
New Finding
Detailed immunohistochemical characterization of temporal and spatial progression of Alzheimer's disease-related pathologies in male triple-transgenic mice.
Mastrangelo MA, Bowers WJ
BMC Neurosci
2008 Aug 12
9
(1):81 [
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Selected by
| Yuan Luo
Evaluated 22 Aug 2008
Must Read
F1000 Factor
6.0
Hypothesis
New Finding
The NALP3 inflammasome is involved in the innate immune response to amyloid-beta.
Halle A, Hornung V, …, Moore KJ, Golenbock DT
Nat Immunol
2008 Aug
9
(8):857-65 [
abstract on PubMed
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Selected by
| Michel Goldman
Evaluated 20 Aug 2008
Must Read
F1000 Factor
6.0
New Finding
Effect of bright light and melatonin on cognitive and noncognitive function in elderly residents of group care facilities: a randomized controlled trial.
Riemersma-van der Lek RF, Swaab DF, …, Hoogendijk WJ, Van Someren EJ
JAMA
2008 Jun 11
299
(22):2642-55 [
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Selected by
| Daniel Kaufer
Evaluated 14 Aug 2008
Must Read
F1000 Factor
6.0
New Finding
Human microglial cells synthesize albumin in brain.
Ahn SM, Byun K, …, Simpson RJ, Lee B
PLoS ONE
2008
3
(7):e2829 [
abstract on PubMed
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Selected by
| Charlotte Teunissen
Evaluated 12 Aug 2008
Recommended
F1000 Factor
3.0
New Finding
A randomized, double-blind, placebo-controlled study of aripiprazole for the treatment of psychosis in nursing home patients with Alzheimer disease.
Streim JE, Porsteinsson AP, …, McQuade R, Carson WH
Am J Geriatr Psychiatry
2008 Jul
16
(7):537-50 [
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Selected by
| David Steffens
Evaluated 8 Aug 2008
Recommended
F1000 Factor
3.0
New Finding
Tech Advance
Longitudinal multimodal imaging in mild to moderate Alzheimer's disease: a pilot study with memantine.
Schmidt R, Ropele S, …, Kolassa H, Fazekas F
J Neurol Neurosurg Psychiatry
2008 Jun 27 [
abstract on PubMed
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Selected by
| David Brooks with Nicola Pavese
Evaluated 1 Aug 2008
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