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Browse > Respiratory Disorders > Asthma & Allergic Rhinitis
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Recommended
F1000 Factor 3.0

Confirmation
 Usefulness of induced sputum in investigating occupational asthma with normal responsiveness to methacholine: A case report.
Yacoub MR, Perfetti L, …, Caminati M, Moscato G
J Allergy Clin Immunol 2008 Sep 12 [abstract on PubMed] [related articles] [full text]
Selected by | Catherine Lemiere
Evaluated 18 Nov 2008

Must Read
F1000 Factor 4.8

Confirmation
Hypothesis
 Association between paracetamol use in infancy and childhood, and risk of asthma, rhinoconjunctivitis, and eczema in children aged 6-7 years: analysis from Phase Three of the ISAAC programme.
Beasley R, Clayton T, …, Stewart A, ISAAC Phase Three Study Group
Lancet 2008 Sep 20 372(9643):1039-48 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Diederick Grobbee with Maroeska M. Rovers / Alexander Moeller
First evaluation 18 Nov 2008 | Latest evaluation 27 Nov 2008


Recommended
F1000 Factor 3.0

Confirmation
 In utero supplementation with methyl donors enhances allergic airway disease in mice.
Hollingsworth JW, Maruoka S, …, Brass DM, Schwartz DA
J Clin Invest 2008 Oct 118(10):3462-9 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Cesar Picado with David Ramos-Barbon
Evaluated 11 Nov 2008


Recommended
F1000 Factor 3.0

Hypothesis
 Identification of pendrin as a common mediator for mucus production in bronchial asthma and chronic obstructive pulmonary disease.
Nakao I, Kanaji S, …, Green ED, Izuhara K
J Immunol 2008 May 1 180(9):6262-9 [abstract on PubMed] [related articles] [order article]
Selected by | Caroline Owen with Sylwia P Lonak
Evaluated 10 Nov 2008


Exceptional
F1000 Factor 9.8

Confirmation
Hypothesis
New Finding
 Effect of 17q21 variants and smoking exposure in early-onset asthma.
Bouzigon E, Corda E, …, Lathrop M, Demenais F
N Engl J Med 2008 Nov 6 359(19):1985-94 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Josep Anto / Lea Bentur with Claudia Lidroneta Costa Katz / Teal Hallstrand
First evaluation 5 Nov 2008 | Latest evaluation 21 Nov 2008

Recommended
F1000 Factor 3.0

New Finding
 Development of regulatory T cells requires IL-7Ralpha stimulation by IL-7 or TSLP.
Mazzucchelli R, Hixon JA, …, Leonard WJ, Durum SK
Blood 2008 Oct 15 112(8):3283-92 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Javier Chinen with Usa Tantibhaedhyangkul
Evaluated 28 Oct 2008

Must Read
F1000 Factor 6.0

Hypothesis
New Finding
 Repressor of GATA regulates TH2-driven allergic airway inflammation and airway hyperresponsiveness.
Hirahara K, Yamashita M, …, Gejyo F, Nakayama T
J Allergy Clin Immunol 2008 Sep 122(3):512-20.e11 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Devendra Agrawal
Evaluated 22 Oct 2008

Must Read
F1000 Factor 6.0

Hypothesis
New Finding
 Corticosteroid-resistant asthma is associated with classical antimicrobial activation of airway macrophages.
Goleva E, Hauk PJ, …, Martin RJ, Leung DY
J Allergy Clin Immunol 2008 Sep 122(3):550-9.e3 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Devendra Agrawal
Evaluated 21 Oct 2008


Recommended
F1000 Factor 3.0

Hypothesis
New Finding
 12/15-Lipoxygenase deficiency protects mice from allergic airways inflammation and increases secretory IgA levels.
Hajek AR, Lindley AR, …, Schleimer RP, Kuperman DA
J Allergy Clin Immunol 2008 Sep 122(3):633-9.e3 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Bruce Levy
Evaluated 17 Oct 2008

Must Read
F1000 Factor 6.4

Confirmation
New Finding
 Management of asthma based on exhaled nitric oxide in addition to guideline-based treatment for inner-city adolescents and young adults: a randomised controlled trial.
Szefler SJ, Mitchell H, …, Curry MD, Busse WW
Lancet 2008 Sep 20 372(9643):1065-72 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Petr Pohunek / Andrew Bush
First evaluation 13 Oct 2008 | Latest evaluation 15 Oct 2008


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