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Browse > Rheumatology & Clinical Immunology > Biomarkers of Rheumatic Disease
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Recommended
F1000 Factor 3.0

Hypothesis
 Inflammatory macrophage migration requires MMP-9 activation by plasminogen in mice.
Gong Y, Hart E, Shchurin A, Hoover-Plow J
J Clin Invest 2008 Aug 1 118 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Rene Toes with Leendert A Trouw
Evaluated 5 Sep 2008

Recommended
F1000 Factor 3.0

Confirmation
New Finding
 Sustained changes in lipid profile and macrophage migration inhibitory factor (MIF) levels after anti-TNF therapy in rheumatoid arthritis.
Wijbrandts CA, van Leuven SI, …, Kastelein JJ, Tak PP
Ann Rheum Dis 2008 Aug 22 [abstract on PubMed] [related articles] [full text]
Selected by | Eric Morand
Evaluated 5 Sep 2008

Must Read
F1000 Factor 6.0

New Finding
 Common variants in DVWA on chromosome 3p24.3 are associated with susceptibility to knee osteoarthritis.
Miyamoto Y, Shi D, …, Jiang Q, Ikegawa S
Nat Genet 2008 Jul 11 [abstract on PubMed] [related articles] [full text]
Selected by | Tim Spector with Frances Williams and Guangju Zhai
Evaluated 1 Aug 2008

Recommended
F1000 Factor 3.0

New Finding
 Can tumor necrosis factor receptor II gene 676T>G polymorphism predict the response grading to anti-TNFalpha therapy in rheumatoid arthritis?
Ongaro A, De Mattei M, …, Trotta F, Padovan M
Rheumatol Int 2008 Jul 28(9):901-8 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Peter Taylor with Sonya Abraham
Author Response | Ongaro A, De Mattei M, Pellati A, Caruso A, Ferretti S, Masieri FF, Fotinidi M, Farina I, Trotta F, Padovan M
Evaluated 8 Jul 2008

Must Read
F1000 Factor 6.0

New Finding
Tech Advance
 Copy number of FCGR3B, which is associated with systemic lupus erythematosus, correlates with protein expression and immune complex uptake.
Willcocks LC, Lyons PA, …, Nash G, Smith KG
J Exp Med 2008 Jun 16 [abstract on PubMed] [related articles] [full text]
Selected by | Rene Toes with Leendert Trouw
Evaluated 4 Jul 2008


Recommended
F1000 Factor 3.0

Tech Advance
 Simplified composite disease activity measures in rheumatoid arthritis: should they be used in standard care?
Bentley MJ, Reed GW
Clin Exp Rheumatol 2008 Mar-Apr 26(2):358-66 [abstract on PubMed] [related articles] [order article]
Selected by | David Scott
Evaluated 2 Jul 2008

Must Read
F1000 Factor 6.0

Hypothesis
Tech Advance
 High IgA rheumatoid factor levels are associated with poor clinical response to tumour necrosis factor alpha inhibitors in rheumatoid arthritis.
Bobbio-Pallavicini F, Caporali R, …, Klersy C, Montecucco C
Ann Rheum Dis 2007 Mar 66(3):302-7 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Guenter Steiner
Evaluated 30 Jun 2008

Recommended
F1000 Factor 3.0

New Finding
 Dramatic regulation of heparanase activity and angiogenesis gene expression in synovium from patients with rheumatoid arthritis.
Li RW, Freeman C, …, Parish CR, Smith PN
Arthritis Rheum 2008 Jun 58(6):1590-600 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Andreas Gruetzkau
Evaluated 23 Jun 2008

Recommended
F1000 Factor 3.2

Hypothesis
New Finding
 Altered expression of MicroRNA in synovial fibroblasts and synovial tissue in rheumatoid arthritis.
Stanczyk J, Pedrioli DM, …, Gay S, Kyburz D
Arthritis Rheum 2008 Apr 58(4):1001-9 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Yuti Chernajovsky / Ladislav Senolt with Maria Filkova
First evaluation 29 May 2008 | Latest evaluation 11 Jun 2008

Recommended
F1000 Factor 3.0

Confirmation
Hypothesis
New Finding
 Lymphoproliferative disease and autoimmunity in mice with increased miR-17-92 expression in lymphocytes.
Xiao C, Srinivasan L, …, Kutok JL, Rajewsky K
Nat Immunol 2008 Apr 9(4):405-14 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Roberto Caricchio
Evaluated 23 May 2008


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