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Browse > Rheumatology & Clinical Immunology > Clinical Immunology
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Must Read
F1000 Factor 6.0

New Finding
 Neisseria meningitidis escape from the bactericidal activity of a monoclonal antibody is mediated by phase variation of lgtG and enhanced by a mutator phenotype.
Bayliss CD, Hoe JC, …, Hood DW, Moxon ER
Infect Immun 2008 Nov 76(11):5038-48 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | William Shafer with Maira Goytia
Evaluated 26 Nov 2008

Recommended
F1000 Factor 3.0

New Finding
 Aryl hydrocarbon receptor regulates Stat1 activation and participates in the development of Th17 cells.
Kimura A, Naka T, …, Fujii-Kuriyama Y, Kishimoto T
Proc Natl Acad Sci U S A 2008 Jul 15 105(28):9721-6 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Ann Reed with Vaidehi R Chowdhary
Evaluated 24 Nov 2008

Must Read
F1000 Factor 6.0

Hypothesis
New Finding
 TLR3 is an endogenous sensor of tissue necrosis during acute inflammatory events.
Cavassani KA, Ishii M, …, Hogaboam CM, Kunkel SL
J Exp Med 2008 Oct 27 205(11):2609-21 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Diego Kyburz
Evaluated 20 Nov 2008


Recommended
F1000 Factor 3.0

New Finding
 Marked differences in fine specificity and isotype usage of the anti-citrullinated protein antibody in health and disease.
Ioan-Facsinay A, Willemze A, …, Huizinga TW, El-Gabalawy HS
Arthritis Rheum 2008 Oct 58(10):3000-8 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Dirk Elewaut
Evaluated 17 Nov 2008

Must Read
F1000 Factor 6.0

Confirmation
Hypothesis
New Finding
 Trex1 prevents cell-intrinsic initiation of autoimmunity.
Stetson DB, Ko JS, Heidmann T, Medzhitov R
Cell 2008 Aug 22 134(4):587-98 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Roberto Caricchio with Stefania Gallucci
Evaluated 14 Nov 2008


Recommended
F1000 Factor 3.0

New Finding
 Epitope spreading to citrullinated antigens in mouse models of autoimmune arthritis and demyelination.
Kidd BA, Ho PP, …, Steinman L, Robinson WH
Arthritis Res Ther 2008 Sep 30 10(5):R119 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Rene Toes with Leendert Trouw
Evaluated 3 Nov 2008

Must Read
F1000 Factor 6.4

New Finding
 CTLA-4 control over Foxp3+ regulatory T cell function.
Wing K, Onishi Y, …, Nomura T, Sakaguchi S
Science 2008 Oct 10 322(5899):271-5 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Ann Reed with Vaidehi R Chowdhary / Gyorgy Nagy
First evaluation 31 Oct 2008 | Latest evaluation 12 Nov 2008


Recommended
F1000 Factor 3.0

Confirmation
 Low-dose ketamine affects immune responses in humans during the early postoperative period.
Beilin B, Rusabrov Y, …, Yardeni IZ, Bessler H
Br J Anaesth 2007 Oct 99(4):522-7 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Marc De Kock with Patrice Forget
Evaluated 28 Oct 2008

Recommended
F1000 Factor 3.0

New Finding
 Development of regulatory T cells requires IL-7Ralpha stimulation by IL-7 or TSLP.
Mazzucchelli R, Hixon JA, …, Leonard WJ, Durum SK
Blood 2008 Oct 15 112(8):3283-92 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Javier Chinen with Usa Tantibhaedhyangkul
Evaluated 28 Oct 2008

Must Read
F1000 Factor 6.5

Hypothesis
New Finding
 Innate immunity and intestinal microbiota in the development of Type 1 diabetes.
Wen L, Ley RE, …, Gordon JI, Chervonsky AV
Nature 2008 Oct 23 455(7216):1109-13 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Philipp M Lepper / Helena Tlaskalova-Hogenova / Kazuhiko Yamamoto with Akiko Okamoto
First evaluation 28 Oct 2008 | Latest evaluation 21 Nov 2008



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