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Immune & Inflammatory Rheumatic Diseases (inc. Arthritis)
Methods, measurements & outcomes in rheumatic disease
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Browse > Rheumatology & Clinical Immunology > Methods, measurements & outcomes in rheumatic disease
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Must Read
F1000 Factor 6.0

Confirmation
 Statins: potentially useful in therapy of systemic sclerosis-related Raynaud's phenomenon and digital ulcers.
Abou-Raya A, Abou-Raya S, Helmii M
J Rheumatol 2008 Sep 35(9):1801-8 [abstract on PubMed] [related articles] [order article]
Selected by | Margitta Worm with Claudia Rasche
Evaluated 1 Dec 2008

Recommended
F1000 Factor 3.0

Confirmation
 The risk of myocardial infarction and pharmacologic and nonpharmacologic myocardial infarction predictors in rheumatoid arthritis: A cohort and nested case-control analysis.
Wolfe F, Michaud K
Arthritis Rheum 2008 Sep 58(9):2612-21 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Martin Aringer with Oleksandr Kleyman
Evaluated 10 Nov 2008

Recommended
F1000 Factor 3.0

New Finding
 Blockade of tumor necrosis factor in collagen-induced arthritis reveals a novel immunoregulatory pathway for Th1 and Th17 cells.
Notley CA, Inglis JJ, …, McNamee KE, Williams RO
J Exp Med 2008 Oct 27 205(11):2491-7 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Carlo Chizzolini
Evaluated 30 Oct 2008

Recommended
F1000 Factor 3.2

New Finding
 Local BAFF gene silencing suppresses Th17-cell generation and ameliorates autoimmune arthritis.
Lai Kwan Lam Q, King Hung Ko O, Zheng BJ, Lu L
Proc Natl Acad Sci U S A 2008 Sep 30 105(39):14993-8 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Wim van den Berg with Marije Koenders / Florence Apparailly with Gabriel Courties
First evaluation 17 Oct 2008 | Latest evaluation 28 Oct 2008

Recommended
F1000 Factor 3.0

New Finding
 Comparison of methotrexate monotherapy with a combination of methotrexate and etanercept in active, early, moderate to severe rheumatoid arthritis (COMET): a randomised, double-blind, parallel treatment trial.
Emery P, Breedveld FC, …, Koenig AS, Freundlich B
Lancet 2008 Aug 2 372(9636):375-82 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Lars Klareskog with Anca I Catrina
Evaluated 7 Oct 2008

Must Read
F1000 Factor 6.4
Articles that inform your practice or change your way of thinking Changes
Clinical Practice

Confirmation
Controversial
 A randomized trial of arthroscopic surgery for osteoarthritis of the knee.
Kirkley A, Birmingham TB, …, Pope JE, Fowler PJ
N Engl J Med 2008 Sep 11 359(11):1097-107 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Geoff Littlejohn / David Hunter
First evaluation 26 Sep 2008 | Latest evaluation 1 Oct 2008

Recommended
F1000 Factor 3.0

New Finding
 Adalimumab with or without methotrexate in juvenile rheumatoid arthritis.
Lovell DJ, Ruperto N, …, Pediatric Rheumatology Collaborative Study Group, Pediatric Rheumatology International Trials Organisation
N Engl J Med 2008 Aug 21 359(8):810-20 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Jiri Vencovsky with Herman Mann
Evaluated 22 Sep 2008

Must Read
F1000 Factor 6.0

Confirmation
 The importance of the baseline Disease Activity Score 28 in determining responders and non-responders to anti-TNF in UK clinical practice.
Smith N, Ding T, …, Gadsby K, Deighton C
Rheumatology (Oxford) 2008 Sep 47(9):1389-91 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | David Scott
Evaluated 18 Sep 2008

Recommended
F1000 Factor 3.0

New Finding
 Upregulated miR-146a expression in peripheral blood mononuclear cells from rheumatoid arthritis patients.
Pauley KM, Satoh M, …, Reeves WH, Chan EK
Arthritis Res Ther 2008 Aug 29 10(4):R101 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Florence Apparailly
Evaluated 16 Sep 2008

Must Read
F1000 Factor 6.0

Hypothesis
 Should subchondral bone turnover be targeted when treating osteoarthritis?
Karsdal MA, Leeming DJ, …, Altman RD, Christiansen C
Osteoarthritis Cartilage 2008 Jun 16(6):638-46 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Yves Henrotin
Evaluated 2 Sep 2008


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