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F1000 Factor 3.0

Tech Advance
Minority HIV-1 Variants in Antiretroviral Naive Persons with Reverse Transcriptase Codon 215 Revertant Mutations.
Mitsuya Y, Varghese V, …, Fessel WJ, Shafer RW
J Virol 2008 Aug 20 [abstract on PubMed] [related articles] [full text]
Selected by | Amalio Telenti
Evaluated 5 Sep 2008

Recommended
F1000 Factor 3.0

New Finding
Controversial
Small interfering RNAs induce macrophage migration inhibitory factor production and proliferation in breast cancer cells via a double-stranded RNA-dependent protein kinase-dependent mechanism.
Armstrong ME, Gantier M, …, Baugh JA, Donnelly SC
J Immunol 2008 Jun 1 180(11):7125-33 [abstract on PubMed] [related articles] [order article]
Selected by | Eric Morand
Evaluated 5 Sep 2008

Recommended
F1000 Factor 3.0

Confirmation
New Finding
Sustained changes in lipid profile and macrophage migration inhibitory factor (MIF) levels after anti-TNF therapy in rheumatoid arthritis.
Wijbrandts CA, van Leuven SI, …, Kastelein JJ, Tak PP
Ann Rheum Dis 2008 Aug 22 [abstract on PubMed] [related articles] [full text]
Selected by | Eric Morand
Evaluated 5 Sep 2008

Must Read
F1000 Factor 6.0

New Finding
Patients With T1 to T2 Breast Cancer With One to Three Positive Nodes Have Higher Local and Regional Recurrence Risks Compared With Node-Negative Patients After Breast-Conserving Surgery and Whole-Breast Radiotherapy.
Truong PT, Jones SO, …, Alexander AS, Olivotto IA
Int J Radiat Oncol Biol Phys 2008 Aug 1 [abstract on PubMed] [related articles] [full text]
Selected by | Alphonse Taghian with Mohamed A Alm El-Din
Evaluated 5 Sep 2008

Recommended
F1000 Factor 3.0

New Finding
A distinct cohort of the TGFbeta superfamily members expressed in human endometrium regulate decidualization.
Stoikos CJ, Harrison CA, Salamonsen LA, Dimitriadis E
Hum Reprod 2008 Jun 23(6):1447-56 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Mark Sullivan
Evaluated 5 Sep 2008

Recommended
F1000 Factor 3.0

Hypothesis
Long-term treatment with finasteride results in a clinically significant reduction in total prostate volume compared to placebo over the full range of baseline prostate sizes in men enrolled in the MTOPS trial.
Kaplan SA, Roehrborn CG, …, Nyberg LM, Medical Therapy of Prostatic Symptoms Research Group
J Urol 2008 Sep 180(3):1030-2; discussion 1032-3 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Eric Rovner with Brett Lebed
Evaluated 5 Sep 2008

Must Read
F1000 Factor 6.0

Confirmation
Care of HIV patients with chronic hepatitis B: updated recommendations from the HIV-Hepatitis B Virus International Panel.
Soriano V, Puoti M, …, Mauss S, Rockstroh J
AIDS 2008 Jul 31 22(12):1399-410 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Reto Nüesch
Evaluated 5 Sep 2008

Recommended
F1000 Factor 3.0

Hypothesis
New Finding
Prospective study evaluating olfactometric and rhinomanometric outcomes in postmenopausal women on 1 mg 17beta-estradiol and 2 mg drospirenone HT.
Caruso S, Serra A, …, Agnello C, Cianci A
Menopause 2008 Jun 10 [abstract on PubMed] [related articles] [full text]
Selected by | Chiara Simonelli with Roberta Rossi
Evaluated 4 Sep 2008

Must Read
F1000 Factor 6.0

New Finding
Gonadotropin-releasing hormone agonists for prevention of chemotherapy-induced ovarian damage: prospective randomized study.
Badawy A, Elnashar A, El-Ashry M, Shahat M
Fertil Steril 2008 Aug 1 [abstract on PubMed] [related articles] [full text]
Selected by | Michael Friedlander
Evaluated 4 Sep 2008

Recommended
F1000 Factor 3.0

Hypothesis
Variation in subfertility care measured by guideline-based performance indicators.
Mourad SM, Nelen WL, …, Grol RP, Kremer JA
Hum Reprod 2008 Jul 24 [abstract on PubMed] [related articles] [full text]
Selected by | Marlies Hulscher
Evaluated 3 Sep 2008


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