M Bruce MacIver

Anesthesia, Stanford University School of Medicine, United States of America

Acknowledgements: Members of the Stanford University Anaesthesia Department provide input and guidance.

Research interests: Neuropharmacology of anesthetics and analgesics
Associations: Society for Neuroscience, AUA, ASA

Any competing interests declared are displayed with individual evaluations.

Faculty Member: Anesthesiology & Pain Management > Anesthetic Mechanisms (since 17 March 2006)

Links

http://www.stanford.edu/group/maciverlab/

All recent recommendations

• 3.2
  Isoflurane is a potent modulator of extrasynaptic GABA(A) receptors in the thalamus.
  Recommended by Robert Dickinson, M Bruce MacIver
  
• 3.0
  Action of dexmedetomidine on the substantia gelatinosa neurons of the rat spinal cord.
  Recommended by M Bruce MacIver
  
• 3.3
  Isoflurane reduces excitability of Drosophila larval motoneurons by activating a hyperpolarizing leak conductance.
  Recommended by Bernd Antkowiak, M Bruce MacIver, Hugh Hemmings
  
• 3.0
  Amnestic concentrations of sevoflurane inhibit synaptic plasticity of hippocampal CA1 neurons through gamma-aminobutyric acid-mediated mechanisms.
  Recommended by M MacIver
  
• 3.0
  Low concentrations of pentobarbital enhance excitability of rat hippocampal neurons.
  Recommended by M MacIver
  
• 3.0
  Neurons in the ventral spinal cord are more depressed by isoflurane, halothane, and propofol than are neurons in the dorsal spinal cord.
  Recommended by M MacIver
  
• 3.0
  Reduced inhibition of cortical glutamate and GABA release by halothane in mice lacking the K+ channel, TREK-1.
  Recommended by M MacIver
  
• 3.0
  Isoflurane bidirectionally modulates the paired-pulse responses in the rat hippocampal CA1 field in vivo.
  Recommended by M MacIver
  
• 4.8
  Differential dynamic of action on cortical and subcortical structures of anesthetic agents during induction of anesthesia.
  Recommended by Valerie Billard, M MacIver
  
• 4.8
  Amnesic concentrations of the nonimmobilizer 1,2-dichlorohexafluorocyclobutane (F6, 2N) and isoflurane alter hippocampal theta oscillations in vivo.
  Recommended by Bernd Antkowiak, M MacIver
  
• 6.4
  Effect of isoflurane and other potent inhaled anesthetics on minimum alveolar concentration, learning, and the righting reflex in mice engineered to express alpha1 gamma-aminobutyric acid type A receptors unresponsive to isoflurane.
  Recommended by M Bruce MacIver, Douglas Raines
  
• 3.0
  Dual actions of enflurane on postsynaptic currents abolished by the gamma-aminobutyric acid type A receptor beta3(N265M) point mutation.
  Recommended by M Bruce MacIver
  
• 4.8
  Effects of isoflurane and enflurane on GABAA and glycine receptors contribute equally to depressant actions on spinal ventral horn neurones in rats.
  Recommended by M Bruce MacIver, Robert Pearce
  
• 6.0
  Bistable network behavior of layer I interneurons in auditory cortex.
  Recommended by M Bruce MacIver
  
• 3.2
  Effects of anesthetics on mutant N-methyl-D-aspartate receptors expressed in Xenopus oocytes.
  Recommended by Douglas Raines, M Bruce MacIver
  
• 3.0
  The differential effects of halothane and isoflurane on windup of dorsal horn neurons selected in unanesthetized decerebrated rats.
  Recommended by M Bruce MacIver
  
• 3.0
  General anesthetics inhibit gap junction communication in cultured organotypic hippocampal slices.
  Recommended by M Bruce MacIver
  
• 3.0
  Contrasting roles of the N-methyl-D-aspartate receptor in the production of immobilization by conventional and aromatic anesthetics.
  Recommended by M Bruce MacIver
  
• 3.0
  Intravenous anesthetics are more effective than volatile anesthetics on inhibitory pathways in rat hippocampal CA1.
  Recommended by M Bruce MacIver
  
• 6.0
  GABA(A)-R alpha1 subunit knockin mutation leads to abnormal EEG and anesthetic-induced seizure-like activity in mice.
  Recommended by M Bruce MacIver
  
• 3.0
  Excitatory and inhibitory actions of isoflurane on the cholinergic ascending arousal system of the rat.
  Recommended by M Bruce MacIver
  
• 3.0
  Volatile anesthetic effects on glutamate versus GABA release from isolated rat cortical nerve terminals: basal release.
  Recommended by M Bruce MacIver