John Rex

AstraZeneca Pharmaceuticals, United Kingdom

BA in Biochemistry, 1975, Rice University, summa cum laude. MD, 1982, Baylor College of Medicine, with Honors. Internal Medicine Residency, Stanford University Hospitals and Clinics, 1984-1987, Fellow in Infectious Diseases, National Institute of Allergy and Infectious Diseases, 1987-1992; Assistant Professor (1992), Associate Professor (1996), and Professor (2001) of Medicine, University of Texas Medical School-Houston. Editor, Antimicrobial Agents and Chemotherapy, co-founder of www.doctorfungus.org , Chair of Clinical Laboratory Standards Institute Subcommittee on Antifungal Susceptibility Testing. Research Interests: Anti-infective agents (antifungal, antibacterial, antimycobacterial), clinical development of novel agents, in vitro and in vivo testing of novel agents, hospital epidemiology and infection control, infections in the critical care setting.

Any competing interests declared are displayed with individual evaluations.

Faculty Member: Infectious Diseases > Nosocomial & Healthcare-Associated Infections (since 14 November 2005)

All recent recommendations

• 3.0
  Prevalence of asymptomatic Tropheryma whipplei carriage among humans and nonhuman primates.
  Recommended by John Rex
  
• 3.0
  Comparison of both clinical features and mortality risk associated with bacteremia due to community-acquired methicillin-resistant Staphylococcus aureus and methicillin-susceptible S. aureus.
  Recommended by John Rex
  
• 3.2
  Are community-associated methicillin-resistant Staphylococcus aureus (MRSA) strains replacing traditional nosocomial MRSA strains?
  Recommended by Allen Cheng, John Rex
  
• 6.0
  Haemophilus haemolyticus: a human respiratory tract commensal to be distinguished from Haemophilus influenzae.
  Recommended by John Rex
  
• 3.0
  Randomized, double-blind, placebo-controlled trial of cephalexin for treatment of uncomplicated skin abscesses in a population at risk for community-acquired methicillin-resistant Staphylococcus aureus infection.
  Recommended by John Rex
  
• 6.0
  An outbreak of poliomyelitis caused by type 1 vaccine-derived poliovirus in China.
  Recommended by John Rex
  
• 6.0
  Enhanced allergic inflammation and airway responsiveness in rats with chronic Cryptococcus neoformans infection: potential role for fungal pulmonary infection in the pathogenesis of asthma.
  Recommended by John Rex
  
• 3.2
  Posaconazole as salvage treatment for invasive fusariosis in patients with underlying hematologic malignancy and other conditions.
  Recommended by Jose Vazquez, John Rex
  
• 3.0
  Staphylococcus aureus carriers neutralize superantigens by antibodies specific for their colonizing strain: a potential explanation for their improved prognosis in severe sepsis.
  Recommended by John Rex
  
• 6.0
  Immune sensing of Candida albicans requires cooperative recognition of mannans and glucans by lectin and Toll-like receptors.
  Recommended by John Rex
  
• 6.0
  The impact of penicillin resistance on short-term mortality in hospitalized adults with pneumococcal pneumonia: a systematic review and meta-analysis.
  Recommended by John Rex
  
• 3.0
  Antifungal prophylaxis with azoles in high-risk, surgical intensive care unit patients: a meta-analysis of randomized, placebo-controlled trials.
  Recommended by John Rex
  
• 6.0
  The anti-Candida vaccine based on the recombinant N-terminal domain of Als1p is broadly active against disseminated candidiasis.
  Recommended by John Rex
  
• 3.0
  Posaconazole as salvage therapy for zygomycosis.
  Recommended by John Rex
  
• 3.0
  Associations between nasal torquetenovirus load and spirometric indices in children with asthma.
  Recommended by John Rex