Joseph Cotten

Massachusetts General Hospital, United States of America

My research focuses on the molecular mechanism by which volatile anesthetics potentiate TASK tandem pore potassium channel function and the role of these pH- and hypoxia-sensitive channels in regulation of breathing. We use an Ussing chamber electrophysiologic system to study these channels and employ a number of molecular techniques, including molecular co-expression, site-directed mutagenesis, and RNA interference. We also use whole-body plethysmography to study breathing.

Any competing interests declared are displayed with individual evaluations.

Faculty Member: Anesthesiology & Pain Management > Airway/Respiratory Physiology (since 05 November 2007)

Links

http://www.massgeneral.org/anesthesia/index.aspx?page=faculty&subpage=cotten

All recent recommendations

• 3.0
  Comparative analysis of neonatal and adult rat carotid body responses to chronic intermittent hypoxia.
  Recommended by Joseph Cotten
  
• 8.0
  Glia-like stem cells sustain physiologic neurogenesis in the adult mammalian carotid body.
  Recommended by Joseph Cotten, Elise Sarton