Luca Persani

Department of Medical Sciences, University of Milan, Italy

Luca Persani is Associate Professor in Endocrinology at the Institute of Endocrine Sciences, School of Medicine of the University of Milan. He heads the Laboratory for Endocrinological Research of IRCCS Istituto Auxologico Italiano.

His research interests focus on the identification and characterization of the biological mechanisms and genes relevant for the development and function of the thyroid gland and the gonads. Particular interest is devoted to the identification and characterization of genetic and molecular mechanisms involved in the pathogenesis of the diseases of thyroid and gonadal axes; the structural and functional characterization of the network of molecular interactions involved in signal transduction processes relevant for thyroid cell function and proliferation; structure-function studies of glycoprotein hormone receptors (GPHRs); factors regulating the biological potency of glycoprotein hormone molecules; and identification of novel markers for diagnosis and follow-up of thyroid and gonadal diseases.

Any competing interests declared are displayed with individual evaluations.

Faculty Member: Diabetes & Endocrinology > Thyroid (since 14 November 2005)

All recent recommendations

• 3.0
  Changed presentation of Hashimoto's thyroiditis in North-Eastern Sicily and Calabria (Southern Italy) based on a 31-year experience.
  Recommended by Luca Persani with Laura Fugazzola
  
• 3.0
  Axitinib Is an Active Treatment for All Histologic Subtypes of Advanced Thyroid Cancer: Results From a Phase II Study.
  Recommended by Luca Persani with Laura Fugazzola
  
• 6.0
  Relations of Thyroid Function to Body Weight: Cross-sectional and Longitudinal Observations in a Community-Based Sample.
  Recommended by Luca Persani
  
• 6.0
  Concentrations of organochlorine pollutants in mothers who gave birth to neonates with congenital hypothyroidism.
  Recommended by Luca Persani
  
• 3.2
  The 22q11 deletion syndrome candidate gene Tbx1 determines thyroid size and positioning.
  Recommended by Luca Persani, Sissy Jhiang
  
• 3.0
  Missense mutations of dual oxidase 2 (DUOX2) implicated in congenital hypothyroidism have impaired trafficking in cells reconstituted with DUOX2 maturation factor.
  Recommended by Luca Persani
  
• 3.0
  Efficacy of rituximab treatment for thyroid-associated ophthalmopathy as a result of intraorbital B-cell depletion in one patient unresponsive to steroid immunosuppression.
  Recommended by Luca Persani
  
• 3.0
  Update of newborn screening and therapy for congenital hypothyroidism.
  Recommended by Luca Persani
  
• 3.0
  A glycoprotein hormone expressed in corticotrophs exhibits unique binding properties on thyroid-stimulating hormone receptor.
  Recommended by Luca Persani
  
• 6.4
  Bile acids induce energy expenditure by promoting intracellular thyroid hormone activation.
  Recommended by Dominique Langin, Luca Persani