Chantal Chenu

Veterinary Basic Sciences, Royal Veterinary College, United Kingdom

Chantal Chenu

Academic positions:
- Senior Lecturer

All industry positions (in last five years):
- None

Research interests:
- My research integrates a range of approaches to investigate the mechanisms by which skeletal innervation and angiogenesis regulate bone development, remodelling and repair. Our main research interests are to establish the role of the sympathetic nervous system (SNS) and the skeletal vascular network during bone modelling and remodeling, both in vitro and in vivo. My group is also involved in the study of the molecular interactions between bone and energy homeostases. Our project explores the role of AMPK, in the control of bone mass and its regulation by leptin. Finally we are actively involved in research in musculoskeletal regenerative medicine and we develop the use of autologous mesenchymal stem cells isolated from bone marrow for distraction osteogenesis.

Any other information:

Any competing interests declared are displayed with individual evaluations.

Faculty Member: Rheumatology & Clinical Immunology > Bone Biology, Osteoporosis & Other Diseases of Bone (since 08 May 2007)

Links

http://www.rvc.ac.uk/Research/Groups/Group1aBone/Index.cfm

All recent recommendations

• 3.0
  Mechanical loading enhances the anabolic effects of intermittent parathyroid hormone (1-34) on trabecular and cortical bone in mice.
  Recommended by Chantal Chenu
  
• 6.0
  Functional Adaptation to Loading of a Single Bone is Neuronally Regulated and Involves Multiple Bones.
  Recommended by Chantal Chenu
  
• 3.0
  Akt1 in osteoblasts and osteoclasts controls bone remodeling.
  Recommended by Chantal Chenu
  
• 6.5
  Self-renewing osteoprogenitors in bone marrow sinusoids can organize a hematopoietic microenvironment.
  Recommended by Chantal Chenu, Gordana Vunjak-Novakovic, Suzanne Watt
  
• 3.0
  Extracellular nucleotides block bone mineralization in vitro: evidence for dual inhibitory mechanisms involving both P2Y2 receptors and pyrophosphate.
  Recommended by Chantal Chenu
  
• 6.8
  Endocrine regulation of energy metabolism by the skeleton.
  Recommended by Carol Pilbeam, Chantal Chenu, Gunter Stalla, Tsutomu Takeuchi
  
• 3.0
  Vascular endothelial growth factor (VEGF)-induced up-regulation of CCN1 in osteoblasts mediates proangiogenic activities in endothelial cells and promotes fracture healing.
  Recommended by Chantal Chenu
  
• 3.0
  Greater bone formation of Y2 knockout mice is associated with increased osteoprogenitor numbers and altered Y1 receptor expression.
  Recommended by Chantal Chenu
  
• 3.0
  Rosiglitazone induces decreases in bone mass and strength that are reminiscent of aged bone.
  Recommended by Chantal Chenu