Dana Gabuzda

Dept of Cancer Immunology & AIDS, Dana-Farber Cancer Institute, United States of America

Any competing interests declared are displayed with individual evaluations.

Faculty Member: Infectious Diseases > HIV Infection & AIDS: Basic Science (since 11 November 2005)

All recent recommendations

• 3.0
  Selective targeting of ITK blocks multiple steps of HIV replication.
  Recommended by Dana Gabuzda with Kevin Olivieri
  
• 3.2
  Identification of host proteins required for HIV infection through a functional genomic screen.
  Recommended by Andrew Badley with Brett D Shepard, Dana Gabuzda with Kevin Olivieri
  
• 4.8
  CCL3L1 and CCR5 influence cell-mediated immunity and affect HIV-AIDS pathogenesis via viral entry-independent mechanisms.
  Recommended by Dana Gabuzda with Kevin Olivieri, Guido Silvestri
  
• 3.0
  The HIV1 protein Vpr acts to promote G2 cell cycle arrest by engaging a DDB1 and Cullin4A-containing ubiquitin ligase complex using VprBP/DCAF1 as an adaptor.
  Recommended by Dana Gabuzda with Kottampatty Rajendran
  
• 4.8
  Intrarectal transmission, systemic infection, and CD4+ T cell depletion in humanized mice infected with HIV-1.
  Recommended by Dana Gabuzda, James Tartaglia
  
• 8.2
  Microbial translocation is a cause of systemic immune activation in chronic HIV infection.
  Recommended by Dana Gabuzda, Rupert Kaul, Eva Guinan, James Tartaglia
  
• 4.8
  PD-1 expression on HIV-specific T cells is associated with T-cell exhaustion and disease progression.
  Recommended by Dana Gabuzda, Vincent Emery
  
• 3.0
  Specific recognition and accelerated uncoating of retroviral capsids by the TRIM5alpha restriction factor.
  Recommended by Dana Gabuzda
  
• 3.0
  Kaposi's sarcoma-associated herpesvirus fusion-entry receptor: cystine transporter xCT.
  Recommended by Dana Gabuzda
  
• 3.0
  Adaptive evolution and antiviral activity of the conserved mammalian cytidine deaminase APOBEC3H.
  Recommended by Dana Gabuzda