Satish Keshav

Gastroenterology, John Radcliffe Hospital, United Kingdom

Research Interests/Other information
Dr Satish Keshav is a specialist physician and gastroenterologist with experience in luminal gastroenterology, hepatology, and liver transplantation. Provides specialist care for IBD at the John Radcliffe Hospital, and runs a busy multi-disciplinary clinic with consultant colleagues, specialist registrars, clinical training and research fellows, and specialist nurses. He provides specialist support for patients at the Lysosomal Storage Disorders Unit at the Royal Free Hospital, which is funded by the National Commissioning Group (NCG).
Dr Keshav's research encompasses laboratory-based investigation of gastrointestinal aspects of immunity and inflammation that is performed in collaboration with colleagues locally, nationally, and internationally, and extends to clinical studies and trials. Thus the research is wide-ranging and translational, aiming to use clinical investigation to understand basic mechanisms, and to take this knowledge into clinical practice. His main interest is in understanding the mechanisms of organ-specific immunity and inflammation in the gastrointestinal tract, and particularly in determining the role of specialised epithelial cells, which maintain host defence and mediate between extrinsic micro-organisms and the innate and adaptive immune systems.

Qualifications:
- FRCP (London) (2004) (MRCP 1995)
- CCST (General internal medicine and Gastroenterology) (2000)
- D. Phil, University of Oxford (1990)
- MBBCh with distinction, University of the Witwatersrand (1985)
- BSc Hons 1st class (Biochemistry and Physiology), University of the Witwatersrand (1984)

Employment:
1/3/2007 - present: Consultant Gastroenterologist, John Radcliffe Hospital, Oxford & Honorary Senior Lecturer, University of Oxford

1/3/2007 - present: Honorary Consultant Physician, Royal Free Hampstead NHS Trust

1/5/2000 - 28/2/2007: Senior Lecturer and Consultant Physician, Royal Free and University College Medical School & Royal Free Hampstead NHS Trust, London

1/5/97 - 30/4/2000: Lecturer and Specialist Registrar, Royal Free and University College Medical School & Royal Free Hampstead NHS Trust

1/5/96 - 30/4/97: Medical Registrar, John Radcliffe Hospital, Oxford

1/10/92-30/4/96: Nuffield Medical Research Fellow, Corpus Christi College, and Research Fellow, Sir William Dunn School of Pathology, University of Oxford

1/10/89-30/9/92: Staines Medical Research Fellow, Exeter College, University of Oxford

1/1/87-31/12/89: D Phil Student & Rhodes Scholar, Balliol College, University of Oxford

1/1/86 -31/12/86: House officer, Hillbrow Hospital, Johannesburg, South Africa

Any competing interests declared are displayed with individual evaluations.

Faculty Member: Gastroenterology & Hepatology > Inflammatory Bowel Disease (since 16 January 2007)

All recent recommendations

• 3.0
  NOD2-expressing bone marrow-derived cells appear to regulate epithelial innate immunity of the transplanted human small intestine.
  Recommended by Satish Keshav
  
• 3.0
  Sox9 regulates cell proliferation and is required for Paneth cell differentiation in the intestinal epithelium.
  Recommended by Satish Keshav
  
• 9.0
  Anti-TNF-alpha therapy induces a distinct regulatory T cell population in patients with rheumatoid arthritis via TGF-beta.
  Recommended by Satish Keshav
  
• 3.0
  Controlled study using wireless capsule endoscopy for the evaluation of the small intestine in chronic refractory pouchitis.
  Recommended by Satish Keshav
  
• 3.0
  SOX9 is required for the differentiation of paneth cells in the intestinal epithelium.
  Recommended by Satish Keshav
  
• 3.0
  A -defensin mutation causes black coat color in domestic dogs.
  Recommended by Satish Keshav
  
• 9.8
  Plasmacytoid dendritic cells sense self-DNA coupled with antimicrobial peptide.
  Recommended by Stefan Martin, Satish Keshav, Michael Schoen