Phyllis Speiser

Division of Pediatric Endocrinology, Schneider Children's Hospital, United States of America

Phyllis W. Speiser is an associate investigator and Director of Pediatric Endocrinology for the North Shore-Long Island Jewish Health System in New York She is co-investigator for ‘The Diabetes & Obesity Intervention Project’ and serves as PI on numerous clinical trials for growth-related drugs.

Dr Speiser’s laboratory has a long-standing interest in disorders of steroid biosynthesis. Her research group has performed extensive studies correlating genotype and phenotype in families with classic and non-classic forms of congenital adrenal hyperplasia.

She currently serves on the Editorial Board of Treatments in Endocrinology.

Any competing interests declared are displayed with individual evaluations.

Faculty Member: Diabetes & Endocrinology > Adrenal Cortex (since 15 November 2005)

Links

http://www.northshorelij.com/body.cfm?id=2703

All recent recommendations

• 3.0
  Variations in the promoter of CYP21A2 gene identified in a Chinese patient with simple virilizing form of 21-hydroxylase deficiency.
  Recommended by Phyllis Speiser
  
• 3.0
  High prevalence of central adrenal insufficiency in patients with Prader-Willi syndrome.
  Recommended by Phyllis Speiser
  
• 3.0
  The Common P450 Oxidoreductase Variant A503V Is Not a Modifier Gene for 21-Hydroxylase Deficiency.
  Recommended by Phyllis Speiser
  
• 3.0
  Anastrozole Increases Predicted Adult Height of Short Adolescent Males Treated with Growth Hormone: A Randomized, Placebo-Controlled, Multicenter Trial for One to Three Years.
  Recommended by Phyllis Speiser
  
• 3.0
  The degree of external genitalia virilization in girls with 21-hydroxylase deficiency appears to be influenced by the CAG repeats in the androgen receptor gene.
  Recommended by Phyllis Speiser
  
• 3.0
  Sexual Orientation in Women with Classical or Non-classical Congenital Adrenal Hyperplasia as a Function of Degree of Prenatal Androgen Excess.
  Recommended by Phyllis Speiser
  
• 3.0
  Testicular adrenal rest tumors and Leydig and Sertoli cell function in boys with classical congenital adrenal hyperplasia.
  Recommended by Phyllis Speiser
  
• 3.0
  Nerve sparing ventral clitoroplasty preserves dorsal nerves in congenital adrenal hyperplasia.
  Recommended by Phyllis Speiser
  
• 3.0
  False negative 17-hydroxyprogesterone screening in children with classical congenital adrenal hyperplasia.
  Recommended by Phyllis Speiser
  
• 3.0
  Apparent manifesting heterozygosity in P450 oxidoreductase deficiency and its effect on coexisting 21-hydroxylase deficiency.
  Recommended by Phyllis Speiser
  
• 3.0
  Reduced final height outcome in congenital adrenal hyperplasia under prednisone treatment: deceleration of growth velocity during puberty.
  Recommended by Phyllis Speiser
  
• 3.0
  Obesity and sex steroid changes across puberty: evidence for marked hyperandrogenemia in pre- and early pubertal obese girls.
  Recommended by Phyllis Speiser
  
• 3.0
  Molecular model of human CYP21 based on mammalian CYP2C5: structural features correlate with clinical severity of mutations causing congenital adrenal hyperplasia.
  Recommended by Phyllis Speiser
  
• 6.0
  Newborn screening fact sheets.
  Recommended by Phyllis Speiser
  
• 3.0
  Anatomical and functional outcomes of feminizing genitoplasty for ambiguous genitalia in patients with virilizing congenital adrenal hyperplasia.
  Recommended by Phyllis Speiser
  
• 3.0
  Heterozygous mutations in natriuretic peptide receptor-B (NPR2) are associated with short stature.
  Recommended by Phyllis Speiser
  
• 3.2
  In humans, early cortisol biosynthesis provides a mechanism to safeguard female sexual development.
  Recommended by Phyllis Speiser, Gerard Conway
  
• 6.0
  Growth hormone (GH) pharmacogenetics: influence of GH receptor exon 3 retention or deletion on first-year growth response and final height in patients with severe GH deficiency.
  Recommended by Phyllis Speiser
  
• 3.0
  Long-term corticosteroid replacement and bone mineral density in adult women with classical congenital adrenal hyperplasia.
  Recommended by Phyllis Speiser
  
• 3.0
  Expression of the human glucocorticoid receptor splice variants alpha, beta, and P in peripheral blood mononuclear leukocytes in healthy controls and in patients with hyper- and hypocortisolism.
  Recommended by Phyllis Speiser