Douglas Raines

Anesthesia, Massachusetts General Hospital, United States of America

Current Appointments: Associate Professor of Anesthesia, Harvard Medical School; Associate Anesthetist, Department of Anesthesia and Critical Care, The Massachusetts General Hospital.

Undergraduate Degree: Chemistry, University of Virginia (1979-83)
Graduate Degree: Medicine, University of Virginia School of Medicine (1983-7)
Internship: Internal Medicine, Albany Medical Center (1987-8)
Residency: Anesthesia, The Massachusetts General Hospital (1988-91)
Research Fellowship: The Massachusetts General Hospital, Harvard Medical School (1991-94)

Associations: American Society of Anesthesiologists, Association of University Anesthesiologists, Biophysical Society, Massachusetts Society of Anesthesiologists, American Association for the Advancement of Science

Research Interests: Molecular mechanisms of anesthetic action, molecular pharmacology, electrophysiological study of 5-HT3, GABAA and NMDA receptors, kinetic modeling of ligand-gated ion channel function, equilibrium and stopped-flow fluorescence spectroscopy.

Any competing interests declared are displayed with individual evaluations.

Faculty Member: Anesthesiology & Pain Management > Anesthetic Mechanisms (since 28 April 2006)

All recent recommendations

• 6.5
  Volatile anesthetic effects on midbrain-elicited locomotion suggest that the locomotor network in the ventral spinal cord is the primary site for immobility.
  Recommended by Douglas Raines with Ken Solt, Hugh Hemmings, Bernd Antkowiak
  
• 8.0
  Competitive inhibition at the glycine site of the N-methyl-D-aspartate receptor by the anesthetics xenon and isoflurane: evidence from molecular modeling and electrophysiology.
  Recommended by Douglas Raines, Andrew Jenkins
  
• 6.4
  Effect of isoflurane and other potent inhaled anesthetics on minimum alveolar concentration, learning, and the righting reflex in mice engineered to express alpha1 gamma-aminobutyric acid type A receptors unresponsive to isoflurane.
  Recommended by M Bruce MacIver, Douglas Raines
  
• 3.2
  Effects of anesthetics on mutant N-methyl-D-aspartate receptors expressed in Xenopus oocytes.
  Recommended by Douglas Raines, M Bruce MacIver