Rubin Tuder

Division of Pulmonary Sciences and Critical Care Medicine, University of Colorado Denver, United States of America

Rubin Tuder is Hart Family Professor of Medicine (Division of Pulmonary Sciences and Critical Care Medicine) and Director of the Program of Translational Lung Research, University of Colorado Denver, School of Medicine. In a secondary appointment, he is also affiliated with the Department of Pathology.

The goal of his research is to uncover mechanisms underlying non-neoplastic lung diseases. To achieve this translational goal, he has focused on both diagnostic and experimental pulmonary pathology. Dr Tuder’s current major research interest is the pathobiology of pulmonary hypertension and emphysema.

Any competing interests declared are displayed with individual evaluations.

Faculty Member: Respiratory Disorders > COPD & Allied Disorders (since 15 November 2005)

All recent recommendations

• 6.0
  Use of mean airspace chord length (Lm) to assess emphysema.
  Recommended by Rubin Tuder
  
• 3.0
  Chronic cigarette smoke causes oxidative damage and apoptosis to retinal pigmented epithelial cells in mice.
  Recommended by Rubin Tuder
  
• 6.0
  Cigarette smoke selectively enhances viral PAMP- and virus-induced pulmonary innate immune and remodeling responses in mice.
  Recommended by Rubin Tuder with Jeong Yun
  
• 3.0
  Altered Nrf2/Keap1-Bach1 equilibrium in pulmonary emphysema.
  Recommended by Rubin Tuder
  
• 3.0
  Increased p53 Level, Bax/BCL-XL Ratio, and TRAIL Receptors Expression in Human Emphysema.
  Recommended by Rubin Tuder
  
• 3.0
  Alveolar macrophage activation and an emphysema-like phenotype in adiponectin deficient mice.
  Recommended by Rubin Tuder
  
• 3.0
  Disruption of p21 Attenuates Lung Inflammation Induced by Cigarette Smoke, LPS and fMLP in Mice.
  Recommended by Rubin Tuder
  
• 6.0
  Squamous metaplasia amplifies pathologic epithelial-mesenchymal interactions in COPD patients.
  Recommended by Rubin Tuder
  
• 6.0
  Alpha1-antitrypsin suppresses TNF-alpha and MMP-12 production by cigarette smoke-stimulated macrophages.
  Recommended by Rubin Tuder
  
• 3.0
  Oxidants in the gas phase of cigarette smoke pass through the lung alveolar wall and raise systemic oxidative stress.
  Recommended by Rubin Tuder
  
• 3.2
  Antielastin autoimmunity in tobacco smoking-induced emphysema.
  Recommended by Rubin Tuder, Don Sin
  
• 3.0
  Cigarette smoke-induced blockade of the mitochondrial respiratory chain switches lung epithelial cell apoptosis into necrosis.
  Recommended by Rubin Tuder
  
• 3.0
  Prostacyclin prevents pulmonary endothelial cell apoptosis induced by cigarette smoke.
  Recommended by Rubin Tuder
  
• 4.8
  IL-18 is induced and IL-18 receptor alpha plays a critical role in the pathogenesis of cigarette smoke-induced pulmonary emphysema and inflammation.
  Recommended by Rubin Tuder, Caroline Owen
  
• 3.0
  Toll-like receptor 4 deficiency causes pulmonary emphysema.
  Recommended by Rubin Tuder
  
• 3.0
  Alveolar Cell Senescence in Pulmonary Emphysema Patients.
  Recommended by Rubin Tuder
  
• 3.0
  Senescence marker protein-30 protects mice lungs from oxidative stress, aging, and smoking.
  Recommended by Rubin Tuder
  
• 3.0
  Adenosine metabolism and murine strain-specific IL-4-induced inflammation, emphysema, and fibrosis.
  Recommended by Rubin Tuder
  
• 6.0
  Micro-CT of the human lung: imaging of alveoli and virtual endoscopy of an alveolar duct in a normal lung and in a lung with centrilobular emphysema--initial observations.
  Recommended by Rubin Tuder
  
• 6.0
  Factor B of the alternative complement pathway regulates development of airway hyperresponsiveness and inflammation.
  Recommended by Rubin Tuder
  
• 6.0
  Structural basis for defects of Keap1 activity provoked by its point mutations in lung cancer.
  Recommended by Rubin Tuder
  
• 3.0
  Identification of vascular progenitor cells in pulmonary arteries of patients with chronic obstructive pulmonary disease.
  Recommended by Rubin Tuder
  
• 6.0
  Circulating haemopoietic and endothelial progenitor cells are decreased in COPD.
  Recommended by Rubin Tuder
  
• 3.0
  Telomere shortening in smokers with and without COPD.
  Recommended by Rubin Tuder
  
• 3.0
  Cigarette smoke-induced pulmonary emphysema in scid-mice. Is the acquired immune system required?
  Recommended by Rubin Tuder
  
• 3.0
  ERK1/2 mitogen-activated protein kinase selectively mediates IL-13-induced lung inflammation and remodeling in vivo.
  Recommended by Rubin Tuder