Judy Kersten

Dept of Anesthesiology, Medical College of Wisconsin, United States of America

Dr. Judy Kersten received her MD from the University of Wisconsin Medical School and completed her Residency in Anesthesiology at the University of Iowa Hospitals and Clinics. Dr. Kersten completed a National Institutes of Health Research Fellowship in Cardiovascular Research at the Medical College of Wisconsin.

Diabetes and hyperglycemia are clear contributors to adverse outcomes in patients at risk for myocardial ischemia, but the mechanisms responsible for this action are poorly understood. The chronic reduction of myocardial oxygen supply, produced by severe coronary artery stenoses leading to coronary occlusion, stimulates growth of collateral vessels that increase blood flow to myocardium at risk for ischemia. Ischemic and anesthetic preconditioning are powerful endogenous mechanisms which protect the myocardium against infarction, independent of alterations in collateral flow. Dr. Kersten's research focuses upon elucidating the mechanisms that positively and negatively modulate the response of myocardium to ischemia and reperfusion injury, including the effects of diabetes and anesthetics on cardioprotective signaling and collateral flow regulation.

Research Interests: Dr. Kersten is interested in myocardial ischemia/reperfusion injury, the coronary circulation, and the effects of diabetes on cardioprotection. Her research is directed at elucidating the mechanisms of anesthetic and ischemic preconditioning and how endogenous signaling pathways are adversely modulated by hyperglycemia.

Memberships: Dr. Kersten is a member of the editorial board of Anesthesiology, and the American Journal of Physiology: Heart and Circulatory Physiology. She has served as chair of the Myocardial Ischemia and Metabolism study section of the National Institutes of Health and as a member of several NIH special empasis panels. Dr. Kersten is a fellow of the American College of Cardiology and a member of the Association of University Anesthesiologists, the American Society of Anesthesiologists and the Society of Cardiovascular Anesthesiologists.

Any competing interests declared are displayed with individual evaluations.

Faculty Member: Anesthesiology & Pain Management > Cardiovascular Medicine in Anesthesia: Basic Science (since 14 November 2005)

Links

http://www.mcw.edu/display/router.asp?docid=13622

All recent recommendations

• 4.9
  Perioperative use of dobutamine in cardiac surgery and adverse cardiac outcome: propensity-adjusted analyses.
  Recommended by Patrick Wouters, Philippe Van der Linden with Robert Tircoveanu, Judy Kersten with Julien Amour
  
• 6.4
  Long-term benefit of postconditioning.
  Recommended by Judy Kersten with Dr Julien Amour, Michael Irwin
  
• 7.6
  Hydrocortisone therapy for patients with septic shock.
  Recommended by Patrick Ray, Judy Kersten with Julien Amour, Greg McAnulty, Martin Dunser, John Laffey, Eric Nylen, Martin Llewelyn, Alain Vuylsteke, Robert Dluhy with Florencia Halperin
  Dissent by Greg Martin, Didier Journois with Guillaume Dubreuil
• 6.0
  Increased mortality, postoperative morbidity, and cost after red blood cell transfusion in patients having cardiac surgery.
  Recommended by Judy Kersten with Dr Julien Amour
  
• 6.4
  Successful use of a 20% lipid emulsion to resuscitate a patient after a presumed bupivacaine-related cardiac arrest.
  Recommended by Anne Lynn, Judy Kersten
  
• 4.9
  Coronary artery stenting and non-cardiac surgery--a prospective outcome study.
  Recommended by Manfred Seeberger, Judy Kersten, Mark Hamilton
  
• 6.0
  Poor intraoperative blood glucose control is associated with a worsened hospital outcome after cardiac surgery in diabetic patients.
  Recommended by Judy Kersten