Alex Evers

Anesthesiology Dept, Washington University School of Medicine, United States of America

Alex S. Evers, M.D.

Academic positions:
- Henry Mallinckrodt Professor of Anesthesiology
- Head of Anesthesiology
- Professor of Internal Medicine
- Professor of Molecular Biology and Pharmacology
- Member of the Institute of Medicine of the National Academy of Sciences
- Board of directors of the Foundation for Anesthesia Research and Education
- Past president of the Association of University Anesthesiologists
- Past chair of the board of directors for the Washington University Faculty Practice Plan.
- Honorary Professor of Anesthesiology and Critical Care at Peking University

Any industry positions (last five years):
None declared

Research interests:
The major focus of Dr Evers' laboratory is elucidation of the molecular mechanism(s) through which anesthetics act to depress nervous system function. He is specifically interested in identifying the target molecules with which anesthetics interact. To identify the specific nervous system proteins with which anesthetics interact, his group have developed photo-labile anesthetic molecules and undertaken photoaffinity labeling studies. Photolabeling studies with fluorinated volatile anesthetics have identified several proteins that contain specific binding sites for the fluorinated volatile anesthetics. More recently, his group have developed an anesthetic steroid that can act as a photolabeling reagent. These reagents have identified several CNS proteins that specifically bind anesthetic steroids including voltage-dependent anion channels (VDAC) and GABA-A receptors. The long-term goals of the lab are to synthesize photolabeling reagents for several classes of anesthetics and to use these agents to classify and characterize the binding sites responsible for producing anesthesia.

Any other information:
Dr Evers is a member of numerous local, national and international committees.

Society memberships include:
- Academy of Anesthesiology Mentors (Founding Member, Executive Council)
- American Association for the Advancement of Science
- American Society of Critical Care Anesthesiologists
- American Society for Pharmacology and Experimental Therapeutics
- American Society of Anesthesiologists
- Association of University Anesthesiologists (President, 2000-2002)
- Association of Anesthesiology Program Directors/Society of Academic Anesthesiology Chairs
- Foundation for Anesthesia Education and Research (Board of Directors 1996-2006)
- International Anesthesia Research Society (Board of Trustees, 2007- present)
- Missouri Society of Anesthesiology
- New York Academy of Sciences
- Society for Ambulatory Anesthesia
- Society of Critical Care Medicine
- Society for Neuroscience
- St. Louis Society of Anesthesiology
- WTG Morton Society (President, 2006- present )

Dr Evers also undertakes a number of editorial responsibilities. He is a member of the editorial board for Journal of Clinical Anesthesia, Journal of Anesthesia and is former editor of the journal 'Anesthesiology'. He is also an Ad hoc manuscript reviewer for the following journals: Biochemical Pharmacology, Circulation, European Journal of Pharmacology, Journal of Clinical Investigation, Science, Journal of Neuroscience, Nature, Biophysical Journal, Journal of Pharmacology and Experimental Therapeutics, Anesthesiology

Dr Evers has received numerous honors, including the American Heart Association Established Investigator Award and a Josiah Macy Foundation Fellowship. He has been a visiting professor at a number of universities within the US, Japan and the UK and in 2007, Dr Evers became an elected fellow of the Academy of Sciences (St Louis)

What I think of the idea behind F1000M:
This website is a convenient and efficient vehicle for identifying the key articles that I need to stay current in my own area as well as in other areas that I like to follow.

Any competing interests declared are displayed with individual evaluations.

Section Head: Anesthesiology & Pain Management > Anesthetic Mechanisms (since 16 November 2005)

Alex Evers is a Section Head for Anesthetic Mechanisms, part of the ANESTHESIOLOGY & PAIN MANAGEMENT Faculty. The role of a Section Head is to work with their Co-Section Head(s) to divide the Section (sub-specialty area) into its component areas of research, nominate leaders in those areas as Faculty Members, and offer ongoing oversight of the content within their Section. They are not asked to evaluate articles, although we do, of course, welcome them.

Links

http://neuroscience.wustl.edu/research/faculty.php?id=36