Cheryl Stucky

Department of Cell Biology, Neurobiology and Anatomy, Medical College Wisconsin, United States of America

Academic positions:
• Assistant Professor
All commercial positions (in last five years):
•
Previous positions (in the last five years):
•
Research interests:
• Cellular and molecular processes through which nociceptors respond to painful force, heat, cold and chemicals
Any other information:

Our goal is to clarify the cellular and molecular processes through which nociceptors respond to painful force, heat, cold and chemicals. We record the physiological responses of identified nociceptors and use immunocytochemical techniques to define specific sub-populations of pain-sensing neurons. These functional techniques are used to analyze knockout mice, transgenic mice and animal models of painful conditions such as peripheral inflammation, nerve injury and diabetic neuropathy. Our unique combination of functional, cellular and molecular techniques allows us to identify the receptors and ion channels and intracellular signaling pathways that underlie the pain that occurs with injury and disease. We hope to determine neural targets that can be used for development of novel pain therapies that have fewer side effects.

Any competing interests declared are displayed with individual evaluations.

Faculty Member: Anesthesiology & Pain Management > Pain: Basic Science (since 11 November 2005)

Links

http://www.mcw.edu/neuroscience/Training/STUCKY.htm

All recent recommendations

• 6.0
  Pungent agents from Szechuan peppers excite sensory neurons by inhibiting two-pore potassium channels.
  Recommended by Cheryl Stucky with Daniel Vilceanu
  
• 6.0
  Parallel "pain" pathways arise from subpopulations of primary afferent nociceptor.
  Recommended by Cheryl Stucky with Daniel Vilceanu
  
• 11.2
  Inhibition of nociceptors by TRPV1-mediated entry of impermeant sodium channel blockers.
  Recommended by Misha Perouansky, Nanna Finnerup, Hugh Hemmings, Emery Brown, Helge Eilers, David Archer, Cheryl Stucky with Daniel Vilceanu, Michael Schaefer
  
• 3.0
  Intense isolectin-B4 binding in rat dorsal root ganglion neurons distinguishes C-fiber nociceptors with broad action potentials and high Nav1.9 expression.
  Recommended by Cheryl Stucky