Hans-Walter Pfister

Klinikum Großhadern, Ludwig-Maximilians-Universität München, Germany

Acknowledgments: Various members of the group assist with making evaluations for Faculty of 1000: Uwe Koedel, Stefan Kastenbauer, Matthias Klein, Robert Paul, Tobias Rupprecht, Bernd Sporer, Stefan Lorenzl, Frank Winkler.

Research interests: Infections of the central nervous system; Mechanisms of traumatic brain injury; Intensive care neurology

Methods used in our laboratory:
-Models of meningitis and labyrintihtis, model of vasogenic brain edema
-Cell culture systems (e.g., cerebral endothelial cells, human granulocytes)
-Measurement of cerebral blood flow using laser Doppler flowmetry, monitoring of intracranial pressure and blood-brain barrier permeability
-RT-PCR, immunohistochemistry, Western blot, chemiluminescence, zymography
-Gene array, Protein array.

Any competing interests declared are displayed with individual evaluations.

: Neurological Disorders > Infectious Diseases of the Nervous System (14 November 2005 - 22 August 2008)

Links

http://www.nefo.med.uni-muenchen.de/mitarbeiter_oberaerzte.shtml

All recent recommendations

• 6.0
  Oral doxycycline versus intravenous ceftriaxone for European Lyme neuroborreliosis: a multicentre, non-inferiority, double-blind, randomised trial.
  Recommended by Hans-Walter Pfister with Uwe Koedel
  
• 3.0
  Genetic deficiency of chemokine receptor CCR5 is a strong risk factor for symptomatic West Nile virus infection: a meta-analysis of 4 cohorts in the US epidemic.
  Recommended by Hans-Walter Pfister with Uwe Koedel
  
• 8.5
  Corticosteroids for bacterial meningitis in adults in sub-Saharan Africa.
  Recommended by Hans-Walter Pfister with Uwe Koedel, Phillip Peterson, Patrick Ray, Anthony Harries, Charles Newton with Samson Gwer
  
• 3.0
  Associative and predictive biomarkers of dementia in HIV-1-infected patients.
  Recommended by Hans-Walter Pfister
  
• 6.0
  Serial MRI to determine the effect of dexamethasone on the cerebral pathology of tuberculous meningitis: an observational study.
  Recommended by Hans-Walter Pfister
  
• 3.0
  Cognitive impairment after cerebral malaria in children: a prospective study.
  Recommended by Hans-Walter Pfister
  
• 6.0
  Detrimental role of delayed antibiotic administration and penicillin-nonsusceptible strains in adult intensive care unit patients with pneumococcal meningitis: the PNEUMOREA prospective multicenter study.
  Recommended by Hans-Walter Pfister
  
• 3.0
  West Nile virus disease: a descriptive study of 228 patients hospitalized in a 4-county region of Colorado in 2003.
  Recommended by Hans-Walter Pfister
  
• 3.0
  Neuropsychological sequelae of bacterial and viral meningitis.
  Recommended by Hans-Walter Pfister
  
• 3.0
  Lethal encephalitis in myeloid differentiation factor 88-deficient mice infected with herpes simplex virus 1.
  Recommended by Hans-Walter Pfister