Guido Silvestri

Hospital of the University of Pennsylvania, United States of America

Any competing interests declared are displayed with individual evaluations.

Faculty Member: Infectious Diseases > HIV Infection & AIDS: Basic Science (since 01 February 2007)

All recent recommendations

• 3.2
  Divergent TLR7 and TLR9 signaling and type I interferon production distinguish pathogenic and nonpathogenic AIDS virus infections.
  Recommended by Guido Silvestri, Genoveffa Franchini with Shari Gordon
  
• 3.2
  Central memory CD8(+) T cells appear to have a shorter lifespan and reduced abundance as a function of HIV disease progression.
  Recommended by Holden Maecker, Guido Silvestri
  
• 6.4
  Relationship between T cell activation and CD4+ T cell count in HIV-seropositive individuals with undetectable plasma HIV RNA levels in the absence of therapy.
  Recommended by William Shearer, Guido Silvestri
  
• 3.0
  Plasmacytoid Dendritic Cell Dynamics and Interferon-{alpha} Production during SIV Infection with a Non-Pathogenic Outcome.
  Recommended by Guido Silvestri
  
• 4.8
  CCL3L1 and CCR5 influence cell-mediated immunity and affect HIV-AIDS pathogenesis via viral entry-independent mechanisms.
  Recommended by Dana Gabuzda with Kevin Olivieri, Guido Silvestri
  
• 4.8
  Suppression of SIV-specific CD4+ T cells by infant but not adult macaque regulatory T cells: implications for SIV disease progression.
  Recommended by Guido Silvestri, James Tartaglia
  
• 3.0
  Low immune activation despite high levels of pathogenic human immunodeficiency virus type 1 results in long-term asymptomatic disease.
  Recommended by Guido Silvestri
  
• 3.0
  MyD88-dependent immune activation mediated by human immunodeficiency virus type 1-encoded Toll-like receptor ligands.
  Recommended by Guido Silvestri
  
• 8.0
  Discovery and optimization of a natural HIV-1 entry inhibitor targeting the gp41 fusion peptide.
  Recommended by Sibylle Schneider-Schaulies, Guido Silvestri
  
• 6.4
  Structural definition of a conserved neutralization epitope on HIV-1 gp120.
  Recommended by Guido Silvestri, James Tartaglia
  
• 8.1
  CD8+ T-cell responses to different HIV proteins have discordant associations with viral load.
  Recommended by Guido Silvestri, Paul Goepfert, William Shearer