Matthew Brown
Musculoskeletal Genetics Group, Diamantina Institute, Australia
Matthew Brown is Professor of Musculoskeletal Genetics at the University of Oxford. In 2005, Professor Brown was appointed to the Chair of Immunogenetics at University of Queensland , based at the Centre for Immunology and Cancer Research, Brisbane. He remains affiliated with the Nuffield Department of Orthopaedic Surgery, where he works in collaboration with Professor Wordsworth on musculoskeletal genetics.
Professor Brown’s research has been in the field of complex rheumatic diseases, in which many genes and environmental factors interact to influence the disease concerned. He has been particularly engaged in researching ankylosing spondylitis, which is the second most common form of inflammatory arthritis worldwide, affecting one in 300 to one in 500 people, making it as common as type one diabetes. It causes progressive fusion of joints, particularly of the spine, and there is currently no known preventive treatment. Professor Brown's group lead a world-wide effort in identifying the other genes involved. His group also research genetic factors involved in osteoporosis, rheumatoid arthritis, and chondrocalcinosis, an extremely common form of arthritis, affecting about 20% of people over 70.
Any competing interests declared are displayed with individual evaluations.
Faculty Member: Diabetes & Endocrinology > Bone & Mineral Metabolism (since 24 August 2007)
Links
http://www.ndos.ox.ac.uk/research/mbrown/
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