Philipp M Lepper

Dept of Intensive Care Medicine, Infection and Immunity Group, University of Bern, Switzerland

Any competing interests declared are displayed with individual evaluations.

Faculty Member: Anesthesiology & Pain Management > Perioperative Hemostasis & Transfusion Medicine (since 09 November 2007)

All recent recommendations

• 6.0
  Toll-like receptor 4 polymorphisms and aspergillosis in stem-cell transplantation.
  Recommended by Philipp M Lepper
  
• 6.5
  Innate immunity and intestinal microbiota in the development of Type 1 diabetes.
  Recommended by Philipp M Lepper, Helena Tlaskalova-Hogenova, Kazuhiko Yamamoto with Akiko Okamoto
  
• 9.7
  Pyogenic bacterial infections in humans with MyD88 deficiency.
  Recommended by John Routes with James Verbsky, Shawn Skerrett, Philipp M Lepper
  
• 6.4
  Catapult-like release of mitochondrial DNA by eosinophils contributes to antibacterial defense.
  Recommended by Philipp M Lepper, Massimo Zeviani with Carlo Viscomi
  
• 8.0
  Mutations in TMPRSS6 cause iron-refractory iron deficiency anemia (IRIDA).
  Recommended by Carlo Brugnara, Philipp M Lepper
  
• 3.0
  Regulation of iron homeostasis by the hypoxia-inducible transcription factors (HIFs).
  Recommended by Philipp M Lepper
  
• 6.0
  The serine protease TMPRSS6 is required to sense iron deficiency.
  Recommended by Philipp M Lepper
  
• 6.0
  NF-kappaB links innate immunity to the hypoxic response through transcriptional regulation of HIF-1alpha.
  Recommended by Philipp M Lepper
  
• 3.0
  Innate immune activation through Nalp3 inflammasome sensing of asbestos and silica.
  Recommended by Philipp M Lepper
  
• 9.0
  Dendritic cell PAR1-S1P3 signalling couples coagulation and inflammation.
  Recommended by Philipp M Lepper
  
• 8.0
  Sequence- and target-independent angiogenesis suppression by siRNA via TLR3.
  Recommended by Philipp M Lepper, Michael McDermott with Yanick Crow
  
• 6.0
  Caspase-8 is activated by cathepsin D initiating neutrophil apoptosis during the resolution of inflammation.
  Recommended by Philipp M Lepper
  
• 6.0
  Kindlin-3 is essential for integrin activation and platelet aggregation.
  Recommended by Philipp M Lepper
  
• 9.0
  TRAM couples endocytosis of Toll-like receptor 4 to the induction of interferon-beta.
  Recommended by Philipp M Lepper
  
• 6.0
  Perfusion-decellularized matrix: using nature's platform to engineer a bioartificial heart.
  Recommended by Philipp M Lepper
  
• 6.0
  Toll-like receptor signalling in macrophages links the autophagy pathway to phagocytosis.
  Recommended by Philipp M Lepper
  
• 6.0
  Akirins are highly conserved nuclear proteins required for NF-kappaB-dependent gene expression in drosophila and mice.
  Recommended by Philipp M Lepper
  
• 6.0
  TAM receptors are pleiotropic inhibitors of the innate immune response.
  Recommended by Philipp M Lepper
  
• 10.1
  TLR4 enhances TGF-beta signaling and hepatic fibrosis.
  Recommended by Ralf Weiskirchen with Falko Drews, Rebecca Wells with Zhaodong Li, Philipp M Lepper, Steven Dooley
  
• 3.0
  Cutting edge: Essential role of hypoxia inducible factor-1alpha in development of lipopolysaccharide-induced sepsis.
  Recommended by Philipp M Lepper