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 CURRENT TOP 10 BY F1000 FACTOR | ALL OF MEDICINE | calculated on 28 August 2008

"Current Top 10 By F1000 Factors" are generated every day using only papers added to F1000 Medicine over the last 30 days. Papers are ranked according to their F1000 Factor which incorporates both the number of times a paper has been evaluated, and the ratings it received. If any papers have an equal F1000 Factor then the most recently added paper is listed first.

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1
Exceptional
F1000 Factor 9.0
Articles that inform your practice or change your way of thinking Changes
Clinical Practice

Confirmation
 Aristolochic acid nephropathy: a worldwide problem.
Debelle FD, Vanherweghem JL, Nortier JL
Kidney Int 2008 Jul 74(2):158-69 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Philippe Lesavre
Evaluated 27 Aug 2008
 
2
Exceptional
F1000 Factor 9.0

Confirmation
New Finding
Controversial
 Emergence and spread of azithromycin-resistant Neisseria gonorrhoeae in Scotland.
Palmer HM, Young H, Winter A, Dave J
J Antimicrob Chemother 2008 Sep 62(3):490-4 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | John Heritage
Evaluated 22 Aug 2008
 
3
Exceptional
F1000 Factor 9.0

New Finding
Tech Advance
 Detection of mutations in EGFR in circulating lung-cancer cells.
Maheswaran S, Sequist LV, …, Toner M, Haber DA
N Engl J Med 2008 Jul 24 359(4):366-77 [abstract on PubMed] [related articles] [FREE full text]
Selected by | John Augoustides
Evaluated 21 Aug 2008

 
4
Exceptional
F1000 Factor 9.0

New Finding
 Proliferation capacity of the renal proximal tubule involves the bulk of differentiated epithelial cells.
Vogetseder A, Picard N, …, Kaissling B, Le Hir M
Am J Physiol Cell Physiol 2008 Jan 294(1):C22-8 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Seymour Rosen
Evaluated 21 Aug 2008
 
5
Exceptional
F1000 Factor 9.0

Confirmation
New Finding
 Colonic crypt organization and tumorigenesis.
Humphries A, Wright NA
Nat Rev Cancer 2008 Jun 8(6):415-24 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Janusz Jankowski
Evaluated 18 Aug 2008
 
6
Exceptional
F1000 Factor 9.0

New Finding
 Influence of methylenetetrahydrofolate reductase gene polymorphisms on homocysteine concentrations after nitrous oxide anesthesia.
Nagele P, Zeugswetter B, …, Mittlböck M, Födinger M
Anesthesiology 2008 Jul 109(1):36-43 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Mike Crowder
Evaluated 14 Aug 2008
 
7
Exceptional
F1000 Factor 9.0

Hypothesis
New Finding
Tech Advance
 Identification of Information Flow-Modulating Drug Targets: A Novel Bridging Paradigm for Drug Discovery.
Hwang WC, Zhang A, Ramanathan M
Clin Pharmacol Ther 2008 Jul 9 [abstract on PubMed] [related articles] [full text]
Selected by | Carlos Morel
Evaluated 14 Aug 2008
 
8
Exceptional
F1000 Factor 9.0

Confirmation
 Reversal of profound, high-dose rocuronium-induced neuromuscular blockade by sugammadex at two different time points: an international, multicenter, randomized, dose-finding, safety assessor-blinded, phase II trial.
Pühringer FK, Rex C, …, Eikermann M, Khuenl-Brady KS
Anesthesiology 2008 Aug 109(2):188-97 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | David Drover
Evaluated 14 Aug 2008
 
9
Exceptional
F1000 Factor 8.6

Hypothesis
New Finding
 Fibroblast growth factor 23 and mortality among patients undergoing hemodialysis.
Gutiérrez OM, Mannstadt M, …, Jüppner H, Wolf M
N Engl J Med 2008 Aug 7 359(6):584-92 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Kamyar Kalantar-Zadeh / Jurg Schifferli with Michael Mayr / Kenneth White with Emily G Farrow / Bradley Dixon / Csaba Kovesdy / Alan Yu with Jeanie Park
First evaluation 14 Aug 2008 | Latest evaluation 26 Aug 2008
 
10
Exceptional
F1000 Factor 8.2

Hypothesis
New Finding
Controversial
 Endometrial NK cells are special immature cells that await pregnancy.
Manaster I, Mizrahi S, …, Yagel S, Mandelboim O
J Immunol 2008 Aug 1 181(3):1869-76 [abstract on PubMed] [related articles] [order article]
Selected by | Vikki Abrahams / Lois Salamonsen / Philippe Le Bouteiller / Judith Bulmer with Gendie E Lash
First evaluation 30 Jul 2008 | Latest evaluation 27 Aug 2008

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