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 CURRENT TOP 10 BY F1000 FACTOR | Neurological Disorders | calculated on 1 December 2008

"Current Top 10 By F1000 Factors" are generated every day using only papers added to F1000 Medicine over the last 30 days. Papers are ranked according to their F1000 Factor which incorporates both the number of times a paper has been evaluated, and the ratings it received. If any papers have an equal F1000 Factor then the most recently added paper is listed first.

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1
Exceptional
F1000 Factor 9.8
Articles that inform your practice or change your way of thinking Changes
Clinical Practice

New Finding
Controversial
Refutation
 Thrombolysis with alteplase 3 to 4.5 hours after acute ischemic stroke.
Hacke W, Kaste M, …, Toni D, ECASS Investigators
N Engl J Med 2008 Sep 25 359(13):1317-29 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Megan Leary with Angela Adams / Bo Norrving / Samuel Stratton
First evaluation 10 Oct 2008 | Latest evaluation 13 Nov 2008
 
2
Exceptional
F1000 Factor 9.0

Confirmation
New Finding
 Dok-7 myasthenia: phenotypic and molecular genetic studies in 16 patients.
Selcen D, Milone M, …, Wieben ED, Engel AG
Ann Neurol 2008 Jul 64(1):71-87 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Richard Lewis
Evaluated 27 Nov 2008
 
3
Exceptional
F1000 Factor 9.0
Articles that inform your practice or change your way of thinking Changes
Clinical Practice

New Finding
 Impact of fever on outcome in patients with stroke and neurologic injury: a comprehensive meta-analysis.
Greer DM, Funk SE, …, Ouzounelli M, Uman GC
Stroke 2008 Nov 39(11):3029-35 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Donald Marion
Evaluated 18 Nov 2008
 
4
Exceptional
F1000 Factor 9.0

Confirmation
 Cranial Autonomic Symptoms in Migraine: Characteristics and Comparison with Cluster Headache.
Lai TH, Fuh JL, Wang SJ
J Neurol Neurosurg Psychiatry 2008 Oct 17 [abstract on PubMed] [related articles] [full text]
Selected by | David Dodick with Todd J Schwedt
Evaluated 14 Nov 2008
 
5
Must Read
F1000 Factor 6.0

Confirmation
 Incidence of early-onset dementias in Cambridgeshire, United Kingdom.
Mercy L, Hodges JR, …, Barker RA, Brayne C
Neurology 2008 Nov 4 71(19):1496-9 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Julene Johnson
Evaluated 1 Dec 2008
 
6
Must Read
F1000 Factor 6.0

Hypothesis
 A randomized trial of dural puncture epidural technique compared with the standard epidural technique for labor analgesia.
Cappiello E, O'Rourke N, Segal S, Tsen LC
Anesth Analg 2008 Nov 107(5):1646-51 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Markus Schneider with Thierry Girard
Evaluated 1 Dec 2008
 
7
Must Read
F1000 Factor 6.0

Confirmation
 Substantial genetic overlap between neurocognition and schizophrenia: genetic modeling in twin samples.
Toulopoulou T, Picchioni M, …, Sham P, Murray R
Arch Gen Psychiatry 2007 Dec 64(12):1348-55 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Heinrich Sauer with Igor Nenadic
Evaluated 27 Nov 2008
 
8
Must Read
F1000 Factor 6.0

New Finding
 Oncogenic mutations in GNAQ occur early in uveal melanoma.
Onken M, Worley LA, …, Bowcock AM, Harbour JW
Invest Ophthalmol Vis Sci 2008 Aug 21 [abstract on PubMed] [related articles] [full text]
Selected by | J Andrew Carlson
Evaluated 26 Nov 2008
 
9
Must Read
F1000 Factor 6.0

Confirmation
 GAB2 alleles modify Alzheimer's risk in APOE epsilon4 carriers.
Reiman EM, Webster JA, …, Papassotiropoulos A, Stephan DA
Neuron 2007 Jun 7 54(5):713-20 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Jean-Charles Lambert with Julien Chapuis
Evaluated 26 Nov 2008
 
10
Must Read
F1000 Factor 6.0

New Finding
 Altered Expression of Genes Involved in GABAergic Transmission and Neuromodulation of Granule Cell Activity in the Cerebellum of Schizophrenia Patients.
Bullock WM, Cardon K, …, Roberts RC, Perrone-Bizzozero NI
Am J Psychiatry 2008 Oct 15 [abstract on PubMed] [related articles] [full text]
Selected by | Francine Benes with Guoqing Sheng
Evaluated 26 Nov 2008

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