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  Sections Covered
Breast Diseases: Benign & Malignant
Cancer in the Elderly
Genitourinary Cancers
Gynecological Cancers
Head & Neck Cancers
Oncology Agents
Pediatric Oncology
Sarcomas
Supportive & Palliative Cancer Care
Related Sections
Adrenal Cortex
Gastrointestinal Cancers
Leukemia & Proliferative Disorders of Hematic Cells
Lung Cancer
Lymphomas & Myelomas
Multiple Endocrine Disorders & Neoplasias
Neuro-Oncology
Skin Cancers (inc. Melanoma & Lymphoma)


 CURRENT TOP 10 BY F1000 FACTOR | Oncology | calculated on 1 December 2008

"Current Top 10 By F1000 Factors" are generated every day using only papers added to F1000 Medicine over the last 30 days. Papers are ranked according to their F1000 Factor which incorporates both the number of times a paper has been evaluated, and the ratings it received. If any papers have an equal F1000 Factor then the most recently added paper is listed first.

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1
Exceptional
F1000 Factor 9.0

New Finding
 Gene expression in fixed tissues and outcome in hepatocellular carcinoma.
Hoshida Y, Villanueva A, …, Llovet JM, Golub TR
N Engl J Med 2008 Nov 6 359(19):1995-2004 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Didier Samuel
Evaluated 24 Nov 2008
 
2
Exceptional
F1000 Factor 9.0

Confirmation
New Finding
 Overexpression of interleukin-1beta induces gastric inflammation and cancer and mobilizes myeloid-derived suppressor cells in mice.
Tu S, Bhagat G, …, Fox JG, Wang TC
Cancer Cell 2008 Nov 4 14(5):408-19 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Richard Peek
Evaluated 14 Nov 2008
 
3
Exceptional
F1000 Factor 9.0

New Finding
 Glycogen synthase kinase 3 in MLL leukaemia maintenance and targeted therapy.
Wang Z, Smith KS, …, Somervaille TC, Cleary ML
Nature 2008 Sep 17 [abstract on PubMed] [related articles] [full text]
Selected by | Jorg Baesecke
Evaluated 30 Oct 2008
 
4
Must Read
F1000 Factor 6.4
Articles that inform your practice or change your way of thinking Changes
Clinical Practice

New Finding
 Defunctioning stoma reduces symptomatic anastomotic leakage after low anterior resection of the rectum for cancer: a randomized multicenter trial.
Matthiessen P, Hallböök O, …, Simert G, Sjödahl R
Ann Surg 2007 Aug 246(2):207-14 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Mattias Soop / Filippo La Torre
First evaluation 13 Nov 2008 | Latest evaluation 26 Nov 2008
 
5
Must Read
F1000 Factor 6.4
Articles that inform your practice or change your way of thinking Changes
Clinical Practice

Confirmation
New Finding
 K-ras mutations and benefit from cetuximab in advanced colorectal cancer.
Karapetis CS, Khambata-Ford S, …, Moore MJ, Zalcberg JR
N Engl J Med 2008 Oct 23 359(17):1757-65 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Nicola Normanno with Antonella De Luca / Jeffrey Evans
Evaluated 25 Nov 2008
 
6
Must Read
F1000 Factor 6.4

New Finding
 Mutations of JAK2 in acute lymphoblastic leukaemias associated with Down's syndrome.
Bercovich D, Ganmore I, …, Green AR, Izraeli S
Lancet 2008 Oct 25 372(9648):1484-92 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Jason Gotlib with Stephen Oh / Neyssa Marina with Maureen M O'Brien
First evaluation 16 Oct 2008 | Latest evaluation 7 Nov 2008
 
7
Must Read
F1000 Factor 6.0

New Finding
 Oncogenic mutations in GNAQ occur early in uveal melanoma.
Onken M, Worley LA, …, Bowcock AM, Harbour JW
Invest Ophthalmol Vis Sci 2008 Aug 21 [abstract on PubMed] [related articles] [full text]
Selected by | J Andrew Carlson
Evaluated 26 Nov 2008
 
8
Must Read
F1000 Factor 6.0

Confirmation
 Adjuvant paclitaxel plus carboplatin compared with observation in stage IB non-small-cell lung cancer: CALGB 9633 with the Cancer and Leukemia Group B, Radiation Therapy Oncology Group, and North Central Cancer Treatment Group Study Groups.
Strauss GM, Herndon JE, …, Vokes EE, Green MR
J Clin Oncol 2008 Nov 1 26(31):5043-51 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Jack West
Evaluated 26 Nov 2008
 
9
Must Read
F1000 Factor 6.0

Confirmation
 Incidence of skin cancers in 3867 patients treated with narrow-band ultraviolet B phototherapy.
Hearn RM, Kerr AC, …, Ferguson J, Dawe RS
Br J Dermatol 2008 Sep 159(4):931-5 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Melvin Chiu
Evaluated 26 Nov 2008
 
10
Must Read
F1000 Factor 6.0

Controversial
 Close or positive margins after mastectomy for DCIS: pattern of relapse and potential indications for radiotherapy.
Rashtian A, Iganej S, Amy Liu IL, Natarajan S
Int J Radiat Oncol Biol Phys 2008 Nov 15 72(4):1016-20 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Alphonse Taghian with Mohamed A Alm El-Din
Evaluated 25 Nov 2008

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