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Biomarkers of Rheumatic Disease
Bone Biology, Osteoporosis & Other Diseases of Bone
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Bone & Mineral Metabolism
Urticaria, Vasculitis & Connective Tissue Disease


 CURRENT TOP 10 BY F1000 FACTOR | Rheumatology & Clinical Immunology | calculated on 1 December 2008

"Current Top 10 By F1000 Factors" are generated every day using only papers added to F1000 Medicine over the last 30 days. Papers are ranked according to their F1000 Factor which incorporates both the number of times a paper has been evaluated, and the ratings it received. If any papers have an equal F1000 Factor then the most recently added paper is listed first.

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1
Exceptional
F1000 Factor 9.9

Hypothesis
New Finding
 Molecular mimicry in pauci-immune focal necrotizing glomerulonephritis.
Kain R, Exner M, …, Rees AJ, Kerjaschki D
Nat Med 2008 Oct 14(10):1088-96 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Heinz Regele / Charles Pusey with Alan Salama / Cees Kallenberg / Philippe Lesavre
First evaluation 21 Oct 2008 | Latest evaluation 17 Nov 2008
 
2
Exceptional
F1000 Factor 9.0

Confirmation
New Finding
Tech Advance
 A functional folate receptor is induced during macrophage activation and can be used to target drugs to activated macrophages.
Xia W, Hilgenbrink AR, …, Cheng JX, Low PS
Blood 2008 Oct 24 [abstract on PubMed] [related articles] [full text]
Selected by | Asok Antony
Evaluated 13 Nov 2008
 
3
Exceptional
F1000 Factor 9.0

New Finding
 Interstitial granulomatous drug reaction to anakinra.
Regula CG, Hennessy J, …, Graber EM, Helm KF
J Am Acad Dermatol 2008 Aug 59(2 Suppl 1):S25-7 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Tetsuo Shiohara
Evaluated 24 Oct 2008
 
4
Must Read
F1000 Factor 6.5

Hypothesis
New Finding
 Innate immunity and intestinal microbiota in the development of Type 1 diabetes.
Wen L, Ley RE, …, Gordon JI, Chervonsky AV
Nature 2008 Oct 23 455(7216):1109-13 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Philipp M Lepper / Helena Tlaskalova-Hogenova / Kazuhiko Yamamoto with Akiko Okamoto
First evaluation 28 Oct 2008 | Latest evaluation 21 Nov 2008

 
5
Must Read
F1000 Factor 6.4

New Finding
 CTLA-4 control over Foxp3+ regulatory T cell function.
Wing K, Onishi Y, …, Nomura T, Sakaguchi S
Science 2008 Oct 10 322(5899):271-5 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Ann Reed with Vaidehi R Chowdhary / Gyorgy Nagy
First evaluation 31 Oct 2008 | Latest evaluation 12 Nov 2008

 
6
Must Read
F1000 Factor 6.0

Confirmation
 Statins: potentially useful in therapy of systemic sclerosis-related Raynaud's phenomenon and digital ulcers.
Abou-Raya A, Abou-Raya S, Helmii M
J Rheumatol 2008 Sep 35(9):1801-8 [abstract on PubMed] [related articles] [order article]
Selected by | Margitta Worm with Claudia Rasche
Evaluated 1 Dec 2008
 
7
Must Read
F1000 Factor 6.0

New Finding
 Neisseria meningitidis escape from the bactericidal activity of a monoclonal antibody is mediated by phase variation of lgtG and enhanced by a mutator phenotype.
Bayliss CD, Hoe JC, …, Hood DW, Moxon ER
Infect Immun 2008 Nov 76(11):5038-48 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | William Shafer with Maira Goytia
Evaluated 26 Nov 2008
 
8
Must Read
F1000 Factor 6.0

Confirmation
 The management of ankle fractures in patients with diabetes.
Wukich DK, Kline AJ
J Bone Joint Surg Am 2008 Jul 90(7):1570-8 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Anwar Marthya with K S Raghavendra
Evaluated 24 Nov 2008
 
9
Must Read
F1000 Factor 6.0

Hypothesis
 Pregabalin and dexamethasone for postoperative pain control: a randomized controlled study in hip arthroplasty.
Mathiesen O, Jacobsen LS, …, Hilsted KL, Dahl JB
Br J Anaesth 2008 Oct 101(4):535-41 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Joel Katz with Hance Clarke
Evaluated 21 Nov 2008
 
10
Must Read
F1000 Factor 6.0

Tech Advance
 High-throughput screening for modulators of mesenchymal stem cell chondrogenesis.
Huang AH, Motlekar NA, …, Shore EM, Mauck RL
Ann Biomed Eng 2008 Nov 36(11):1909-21 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Jason Burdick with Cindy Chung
Evaluated 20 Nov 2008

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