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Acute Cardiovascular Problems
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Acute Renal Failure
Heart Failure
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 ALL TIME TOP 10 BY F1000 FACTOR | Critical Care & Emergency Medicine | calculated on 1 December 2008

All Time Top 10 By F1000 Factors are generated every day using papers added to F1000 Medicine since the project started (Top 10s consider papers evaluated in the preceding month). Papers are ranked according to their F1000 Factor which incorporates both the number of times a paper has been evaluated, and the ratings it received. If any papers have an equal F1000 Factor then the most recently added paper is listed first.

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1
Exceptional
F1000 Factor 11.5
Articles that inform your practice or change your way of thinking Changes
Clinical Practice

Confirmation
Hypothesis
New Finding
Controversial
Refutation
 Anesthesia awareness and the bispectral index.
Avidan MS, Zhang L, …, Jacobsohn E, Evers AS
N Engl J Med 2008 Mar 13 358(11):1097-108 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Vesna Jevtovic-Todorovic / Philippa Newfield / Beverley Orser / Emery Brown / Harald Groeben / Benedikt Pannen / Manfred Seeberger / Alain Borgeat / Lynda Wells / Dhanesh Gupta / Alex Sia with Serene Leo / Paul Barash / Michael O'Connor / Masahiko Kawaguchi
Dissenters | Albert Dahan with Elise Sarton / Ville Jantti with Seppo Alahuhta
Author Response | Avidan MS, Zhang L, Burnside BA, Finkel KJ, Searleman AC, Selvidge JA, Saager L, Turner MS, Rao S, Bottros M, Hantler C, Jacobsohn E, Evers AS. B-Unaware Trial Group / Avidan et al. [2] / Avidan et al. [3] / Avidan et al. [4] / Avidan et al. [5] / Avidan et al. [13] / Avidan et al. [12] / Avidan et al. [6] / Avidan et al. [7] / Avidan et al. [14] / Avidan et al. [8] / Avidan et al. [9] / Avidan et al. [10] / Avidan et al. [11]
First evaluation 18 Mar 2008 | Latest evaluation 11 Jun 2008

 
2
Exceptional
F1000 Factor 10.5
Articles that inform your practice or change your way of thinking Changes
Clinical Practice

Confirmation
Hypothesis
New Finding
Controversial
Refutation
 Intensity of renal support in critically ill patients with acute kidney injury.
VA/NIH Acute Renal Failure Trial Network, Palevsky PM, …, Star RA, Peduzzi P
N Engl J Med 2008 Jul 3 359(1):7-20 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Achim Joerres / Andrew Davenport / John Laffey / Greg Martin / Giuseppe Remuzzi with Arrigo Schieppati / Heleen Oudemans-van Straaten / William Mitch
First evaluation 2 Jun 2008 | Latest evaluation 14 Aug 2008
 
3
Exceptional
F1000 Factor 10.2
Articles that inform your practice or change your way of thinking Changes
Clinical Practice

Confirmation
Hypothesis
New Finding
Controversial
 Comparison of two fluid-management strategies in acute lung injury.
National Heart, Lung, and Blood Institute Acute Respiratory Distress Syndrome (ARDS) Clinical Trials Network, Wiedemann HP, …, Hite RD, Harabin AL
N Engl J Med 2006 Jun 15 354(24):2564-75 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Lynne Warner Stevenson / Jacques Lacroix / Greg Martin / Michael Gropper / Jacob Sznajder
First evaluation 10 Aug 2006 | Latest evaluation 22 May 2007
 
4
Exceptional
F1000 Factor 10.0
Articles that inform your practice or change your way of thinking Changes
Clinical Practice

Confirmation
New Finding
Controversial
 Efficacy and safety of a paired sedation and ventilator weaning protocol for mechanically ventilated patients in intensive care (Awakening and Breathing Controlled trial): a randomised controlled trial.
Girard TD, Kress JP, …, Bernard GR, Ely EW
Lancet 2008 Jan 12 371(9607):126-34 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Ognjen Gajic / Christer Sinderby / Paolo Navalesi with Dr Valentina Bergamaschi / Jim O'Brien / Marjolein de Wit
First evaluation 21 Jan 2008 | Latest evaluation 6 May 2008
 
5
Exceptional
F1000 Factor 9.8
Articles that inform your practice or change your way of thinking Changes
Clinical Practice

New Finding
Controversial
Refutation
 Thrombolysis with alteplase 3 to 4.5 hours after acute ischemic stroke.
Hacke W, Kaste M, …, Toni D, ECASS Investigators
N Engl J Med 2008 Sep 25 359(13):1317-29 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Megan Leary with Angela Adams / Bo Norrving / Samuel Stratton
First evaluation 10 Oct 2008 | Latest evaluation 13 Nov 2008
 
6
Exceptional
F1000 Factor 9.8
Articles that inform your practice or change your way of thinking Changes
Clinical Practice

Confirmation
Hypothesis
New Finding
Controversial
 Rhythm control versus rate control for atrial fibrillation and heart failure.
Roy D, Talajic M, …, Waldo AL, Atrial Fibrillation and Congestive Heart Failure Investigators
N Engl J Med 2008 Jun 19 358(25):2667-77 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Brian Olshansky with Chirag Sandesara / Wilbert Aronow / Hector Ventura with Anil Verma
First evaluation 15 Jul 2008 | Latest evaluation 11 Aug 2008
 
7
Exceptional
F1000 Factor 9.8
Articles that inform your practice or change your way of thinking Changes
Clinical Practice

Confirmation
Controversial
 Pulmonary-artery versus central venous catheter to guide treatment of acute lung injury.
National Heart, Lung, and Blood Institute Acute Respiratory Distress Syndrome (ARDS) Clinical Trials Network, Wheeler AP, …, Hite RD, Harabin AL
N Engl J Med 2006 May 25 354(21):2213-24 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Greg Martin / Yoram Weiss / Michael Gropper
First evaluation 16 Jun 2006 | Latest evaluation 4 Oct 2006
 
8
Exceptional
F1000 Factor 9.0
Articles that inform your practice or change your way of thinking Changes
Clinical Practice

New Finding
 Impact of fever on outcome in patients with stroke and neurologic injury: a comprehensive meta-analysis.
Greer DM, Funk SE, …, Ouzounelli M, Uman GC
Stroke 2008 Nov 39(11):3029-35 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Donald Marion
Evaluated 18 Nov 2008
 
9
Exceptional
F1000 Factor 9.0

Confirmation
 Septic impairment of capillary blood flow requires nicotinamide adenine dinucleotide phosphate oxidase but not nitric oxide synthase and is rapidly reversed by ascorbate through an endothelial nitric oxide synthase-dependent mechanism.
Tyml K, Li F, Wilson JX
Crit Care Med 2008 Aug 36(8):2355-62 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Heleen Oudemans-van Straaten
Evaluated 10 Sep 2008
 
10
Exceptional
F1000 Factor 9.0

New Finding
 Essential roles of PI(3)K-p110beta in cell growth, metabolism and tumorigenesis.
Jia S, Liu Z, …, Roberts TM, Zhao JJ
Nature 2008 Aug 7 454(7205):776-9 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Marc Jeschke
Evaluated 29 Aug 2008

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