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Biliary Tract
Clinical Nutrition
Colon & Rectum
Disorders of Neurogastroenterology & Motility
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Pancreas
Small Intestine
Stomach & Duodenum
Related Sections
Diabetes & Obesity
Renal & Gastrointestinal Problems in Critical Care


 ALL TIME TOP 10 BY F1000 FACTOR | Gastroenterology & Hepatology | calculated on 1 December 2008

All Time Top 10 By F1000 Factors are generated every day using papers added to F1000 Medicine since the project started (Top 10s consider papers evaluated in the preceding month). Papers are ranked according to their F1000 Factor which incorporates both the number of times a paper has been evaluated, and the ratings it received. If any papers have an equal F1000 Factor then the most recently added paper is listed first.

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1
Exceptional
F1000 Factor 10.5
Articles that inform your practice or change your way of thinking Changes
Clinical Practice

Confirmation
Hypothesis
New Finding
Controversial
Refutation
 Intensity of renal support in critically ill patients with acute kidney injury.
VA/NIH Acute Renal Failure Trial Network, Palevsky PM, …, Star RA, Peduzzi P
N Engl J Med 2008 Jul 3 359(1):7-20 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Achim Joerres / Andrew Davenport / John Laffey / Greg Martin / Giuseppe Remuzzi with Arrigo Schieppati / Heleen Oudemans-van Straaten / William Mitch
First evaluation 2 Jun 2008 | Latest evaluation 14 Aug 2008
 
2
Exceptional
F1000 Factor 10.1

New Finding
Tech Advance
 TLR4 enhances TGF-beta signaling and hepatic fibrosis.
Seki E, De Minicis S, …, Brenner DA, Schwabe RF
Nat Med 2007 Nov 13(11):1324-32 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Ralf Weiskirchen with Falko Drews / Rebecca Wells with Zhaodong Li / Philipp M Lepper / Steven Dooley
First evaluation 27 Nov 2007 | Latest evaluation 13 Dec 2007
 
3
Exceptional
F1000 Factor 9.9

Hypothesis
New Finding
Tech Advance
 Senescence of activated stellate cells limits liver fibrosis.
Krizhanovsky V, Yon M, …, Zender L, Lowe SW
Cell 2008 Aug 22 134(4):657-67 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Ralf Weiskirchen with Jens Herrmann / Rebecca Wells / Steven Dooley
First evaluation 9 Sep 2008 | Latest evaluation 19 Nov 2008
 
4
Exceptional
F1000 Factor 9.8

Hypothesis
New Finding
Controversial
 Plasmacytoid dendritic cells sense self-DNA coupled with antimicrobial peptide.
Lande R, Gregorio J, …, Liu YJ, Gilliet M
Nature 2007 Oct 4 449(7162):564-9 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Stefan Martin / Satish Keshav / Michael Schoen
First evaluation 15 Oct 2007 | Latest evaluation 11 Feb 2008

 
5
Exceptional
F1000 Factor 9.6

Confirmation
 Controversies of total mesorectal excision for rectal cancer in elderly patients.
Rutten HJ, den Dulk M, …, van de Velde CJ, Marijnen CA
Lancet Oncol 2008 May 9(5):494-501 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Riccardo Audisio / Filippo La Torre
Author Response | Rutten HJ, den Dulk M, Lemmens VE, van de Velde CJ, Marijnen CA
First evaluation 23 May 2008 | Latest evaluation 11 Jun 2008
 
6
Exceptional
F1000 Factor 9.0

New Finding
 Gene expression in fixed tissues and outcome in hepatocellular carcinoma.
Hoshida Y, Villanueva A, …, Llovet JM, Golub TR
N Engl J Med 2008 Nov 6 359(19):1995-2004 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Didier Samuel
Evaluated 24 Nov 2008
 
7
Exceptional
F1000 Factor 9.0

Confirmation
New Finding
 Overexpression of interleukin-1beta induces gastric inflammation and cancer and mobilizes myeloid-derived suppressor cells in mice.
Tu S, Bhagat G, …, Fox JG, Wang TC
Cancer Cell 2008 Nov 4 14(5):408-19 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Richard Peek
Evaluated 14 Nov 2008
 
8
Exceptional
F1000 Factor 9.0

New Finding
 The impact of hospital-acquired infection on outcome in acute pancreatitis.
Wu BU, Johannes RS, Kurtz S, Banks PA
Gastroenterology 2008 Sep 135(3):816-20 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Matthew DiMagno with Anthony T DeBenedet
Evaluated 30 Oct 2008
 
9
Exceptional
F1000 Factor 9.0

Confirmation
 Barrett's esophagus on repeat endoscopy: should we look more than once?
Rodriguez S, Mattek N, …, Fennerty B, Eisen G
Am J Gastroenterol 2008 Aug 103(8):1892-7 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Prateek Sharma with Neil Gupta
Evaluated 27 Oct 2008
 
10
Exceptional
F1000 Factor 9.0

New Finding
 LXR signaling couples sterol metabolism to proliferation in the acquired immune response.
Bensinger SJ, Bradley MN, …, Jamieson BD, Tontonoz P
Cell 2008 Jul 11 134(1):97-111 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Percy Knolle
Evaluated 15 Oct 2008


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