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Anemias & Hypocellular Marrow Disorders
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Perioperative Hemostasis & Transfusion Medicine


 ALL TIME TOP 10 BY F1000 FACTOR | Hematology | calculated on 1 December 2008

All Time Top 10 By F1000 Factors are generated every day using papers added to F1000 Medicine since the project started (Top 10s consider papers evaluated in the preceding month). Papers are ranked according to their F1000 Factor which incorporates both the number of times a paper has been evaluated, and the ratings it received. If any papers have an equal F1000 Factor then the most recently added paper is listed first.

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1
Exceptional
F1000 Factor 9.6

New Finding
 Programmed anuclear cell death delimits platelet life span.
Mason KD, Carpinelli MR, …, Huang DC, Kile BT
Cell 2007 Mar 23 128(6):1173-86 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Neil Kaplowitz / Chris Prowse
First evaluation 23 Apr 2007 | Latest evaluation 20 Jun 2007

 
2
Exceptional
F1000 Factor 9.0

Confirmation
New Finding
Tech Advance
 A functional folate receptor is induced during macrophage activation and can be used to target drugs to activated macrophages.
Xia W, Hilgenbrink AR, …, Cheng JX, Low PS
Blood 2008 Oct 24 [abstract on PubMed] [related articles] [full text]
Selected by | Asok Antony
Evaluated 13 Nov 2008
 
3
Exceptional
F1000 Factor 9.0

New Finding
 Glycogen synthase kinase 3 in MLL leukaemia maintenance and targeted therapy.
Wang Z, Smith KS, …, Somervaille TC, Cleary ML
Nature 2008 Sep 17 [abstract on PubMed] [related articles] [full text]
Selected by | Jorg Baesecke
Evaluated 30 Oct 2008
 
4
Exceptional
F1000 Factor 9.0

Hypothesis
New Finding
 Direct intrabone transplant of unrelated cord-blood cells in acute leukaemia: a phase I/II study.
Frassoni F, Gualandi F, …, Labopin M, Bacigalupo A
Lancet Oncol 2008 Sep 9(9):831-9 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Bruce Camitta with Julie Talano
Evaluated 17 Sep 2008
 
5
Exceptional
F1000 Factor 9.0

Tech Advance
 TINF2, a component of the shelterin telomere protection complex, is mutated in dyskeratosis congenita.
Savage SA, Giri N, …, Lansdorp PM, Alter BP
Am J Hum Genet 2008 Feb 82(2):501-9 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Christian Kratz
Evaluated 1 Aug 2008

 
6
Exceptional
F1000 Factor 9.0

New Finding
 A role of phosphatidylserine externalization in clearance of erythrocytes exposed to stress but not in eliminating aging populations of erythrocyte in mice.
Khandelwal S, Saxena RK
Exp Gerontol 2008 May 11 [abstract on PubMed] [related articles] [full text]
Selected by | Hans U Lutz
Evaluated 30 Jun 2008
 
7
Exceptional
F1000 Factor 9.0

Hypothesis
New Finding
 Mutations in EKLF/KLF1 form the molecular basis of the rare blood group In(Lu) phenotype.
Singleton BK, Burton NM, …, Brady RL, Anstee DJ
Blood 2008 May 16 [abstract on PubMed] [related articles] [full text]
Selected by | Marilyn Telen
Evaluated 6 Jun 2008
 
8
Exceptional
F1000 Factor 9.0
Articles that inform your practice or change your way of thinking Changes
Clinical Practice

Confirmation
Hypothesis
New Finding
 Initiating and cancer-propagating cells in TEL-AML1-associated childhood leukemia.
Hong D, Gupta R, …, Greaves M, Enver T
Science 2008 Jan 18 319(5861):336-9 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Zhu Chen with Jiang Zhu
Evaluated 9 Apr 2008

 
9
Exceptional
F1000 Factor 9.0

Confirmation
 von Willebrand disease (VWD): evidence-based diagnosis and management guidelines, the National Heart, Lung, and Blood Institute (NHLBI) Expert Panel report (USA).
Nichols WL, Hultin MB, …, Weinstein M, Yawn BP
Haemophilia 2008 Mar 14(2):171-232 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Margaret Ragni
Evaluated 19 Mar 2008
 
10
Exceptional
F1000 Factor 9.0

New Finding
 Hydroxyurea attenuates activated neutrophil-mediated sickle erythrocyte membrane phosphatidylserine exposure and adhesion to pulmonary vascular endothelium.
Haynes J, Obiako B, …, Baliga BS, Stevens T
Am J Physiol Heart Circ Physiol 2008 Jan 294(1):H379-85 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Hans U Lutz
Evaluated 17 Jan 2008

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