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Antimicrobials & Drug Resistance
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HIV Infection & AIDS: Basic Science
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Gastrointestinal Infections
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Infectious Diseases of the Nervous System
Respiratory Infections
Skin Infections (inc. STDs)
Urological Infections


 ALL TIME TOP 10 BY F1000 FACTOR | Infectious Diseases | calculated on 1 December 2008

All Time Top 10 By F1000 Factors are generated every day using papers added to F1000 Medicine since the project started (Top 10s consider papers evaluated in the preceding month). Papers are ranked according to their F1000 Factor which incorporates both the number of times a paper has been evaluated, and the ratings it received. If any papers have an equal F1000 Factor then the most recently added paper is listed first.

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1
Exceptional
F1000 Factor 10.2

Confirmation
Hypothesis
New Finding
Tech Advance
 Clonal integration of a polyomavirus in human Merkel cell carcinoma.
Feng H, Shuda M, Chang Y, Moore PS
Science 2008 Feb 22 319(5866):1096-100 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Sabine Kohler / Ulrike Blume-Peytavi with Karola Stieler / Isaac Neuhaus / Juergen Becker / Jane Sterling
First evaluation 31 Jan 2008 | Latest evaluation 12 Nov 2008

 
2
Exceptional
F1000 Factor 9.7

Confirmation
New Finding
 Pyogenic bacterial infections in humans with MyD88 deficiency.
von Bernuth H, Picard C, …, Puel A, Casanova JL
Science 2008 Aug 1 321(5889):691-6 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | John Routes with James Verbsky / Shawn Skerrett / Philipp M Lepper
First evaluation 28 Aug 2008 | Latest evaluation 25 Sep 2008

 
3
Exceptional
F1000 Factor 9.6

Hypothesis
New Finding
 Persistent activation of an innate immune response translates respiratory viral infection into chronic lung disease.
Kim EY, Battaile JT, …, Peltz G, Holtzman MJ
Nat Med 2008 Jun 14(6):633-40 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Rosalind Smyth / Caroline Owen
First evaluation 25 Jun 2008 | Latest evaluation 30 Jun 2008

 
4
Exceptional
F1000 Factor 9.0

New Finding
 Acyclovir is activated into a HIV-1 reverse transcriptase inhibitor in herpesvirus-infected human tissues.
Lisco A, Vanpouille C, …, Schinazi RF, Margolis L
Cell Host Microbe 2008 Sep 11 4(3):260-70 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Guy de Bruyn
Evaluated 18 Sep 2008
 
5
Exceptional
F1000 Factor 9.0

Confirmation
New Finding
Controversial
 Emergence and spread of azithromycin-resistant Neisseria gonorrhoeae in Scotland.
Palmer HM, Young H, Winter A, Dave J
J Antimicrob Chemother 2008 Sep 62(3):490-4 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | John Heritage
Evaluated 22 Aug 2008
 
6
Exceptional
F1000 Factor 9.0

Hypothesis
 Critical issues in mucosal immunity for HIV-1 vaccine development.
Haynes BF, Shattock RJ
J Allergy Clin Immunol 2008 May 9 [abstract on PubMed] [related articles] [full text]
Selected by | William Shearer
Evaluated 9 Jul 2008
 
7
Exceptional
F1000 Factor 9.0

New Finding
 Differences in global gene expression in peripheral blood mononuclear cells indicate a significant role of the innate responses in progression of dengue fever but not dengue hemorrhagic fever.
Ubol S, Masrinoul P, …, Charoensirisuthikul T, Kasisith J
J Infect Dis 2008 May 15 197(10):1459-67 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Scott Halstead
Evaluated 2 Jul 2008
 
8
Exceptional
F1000 Factor 9.0

Hypothesis
New Finding
Controversial
 Misoprostol Impairs Female Reproductive Tract Innate Immunity against Clostridium sordellii.
Aronoff DM, Hao Y, …, Brock TG, Peters-Golden M
J Immunol 2008 Jun 15 180(12):8222-30 [abstract on PubMed] [related articles] [order article]
Selected by | Steven Witkin
Evaluated 24 Jun 2008
 
9
Exceptional
F1000 Factor 9.0

Confirmation
Hypothesis
New Finding
Tech Advance
 Detection of intracellular bacterial communities in human urinary tract infection.
Rosen DA, Hooton TM, …, Humphrey PA, Hultgren SJ
PLoS Med 2007 Dec 4(12):e329 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Daniel Lew
Evaluated 12 Jun 2008
 
10
Exceptional
F1000 Factor 9.0

Confirmation
 A Longitudinal Study of Vaginal Douching and Bacterial Vaginosis--A Marginal Structural Modeling Analysis.
Brotman RM, Klebanoff MA, …, Zenilman JM, Scharfstein DO
Am J Epidemiol 2008 May 23 [abstract on PubMed] [related articles] [full text]
Selected by | Jack Sobel
Evaluated 3 Jun 2008

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