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 ALL TIME TOP 10 BY F1000 FACTOR | Neurological Disorders | calculated on 1 December 2008

All Time Top 10 By F1000 Factors are generated every day using papers added to F1000 Medicine since the project started (Top 10s consider papers evaluated in the preceding month). Papers are ranked according to their F1000 Factor which incorporates both the number of times a paper has been evaluated, and the ratings it received. If any papers have an equal F1000 Factor then the most recently added paper is listed first.

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1
Exceptional
F1000 Factor 11.2

Confirmation
Hypothesis
New Finding
Tech Advance
 Inhibition of nociceptors by TRPV1-mediated entry of impermeant sodium channel blockers.
Binshtok AM, Bean BP, Woolf CJ
Nature 2007 Oct 4 449(7162):607-10 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Misha Perouansky / Nanna Finnerup / Hugh Hemmings / Emery Brown / Helge Eilers / David Archer / Cheryl Stucky with Daniel Vilceanu / Michael Schaefer
First evaluation 23 Oct 2007 | Latest evaluation 13 Mar 2008

 
2
Exceptional
F1000 Factor 9.8
Articles that inform your practice or change your way of thinking Changes
Clinical Practice

New Finding
Controversial
Refutation
 Thrombolysis with alteplase 3 to 4.5 hours after acute ischemic stroke.
Hacke W, Kaste M, …, Toni D, ECASS Investigators
N Engl J Med 2008 Sep 25 359(13):1317-29 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Megan Leary with Angela Adams / Bo Norrving / Samuel Stratton
First evaluation 10 Oct 2008 | Latest evaluation 13 Nov 2008
 
3
Exceptional
F1000 Factor 9.8

Hypothesis
New Finding
 BDNF from microglia causes the shift in neuronal anion gradient underlying neuropathic pain.
Coull JA, Beggs S, …, Salter MW, De Koninck Y
Nature 2005 Dec 15 438(7070):1017-21 [abstract on PubMed] [related articles] [order article]
Selected by | Hanns Ulrich Zeilhofer / Arthur Craig / Jürgen Sandkühler
First evaluation 13 Jun 2006 | Latest evaluation 17 Aug 2006

 
4
Exceptional
F1000 Factor 9.6

Confirmation
Hypothesis
New Finding
 Cortico-striatal synaptic defects and OCD-like behaviours in Sapap3-mutant mice.
Welch JM, Lu J, …, Wetsel WC, Feng G
Nature 2007 Aug 23 448(7156):894-900 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | X.William Yang / Daniel Geschwind
First evaluation 5 Oct 2007 | Latest evaluation 17 Oct 2007

 
5
Exceptional
F1000 Factor 9.6

Hypothesis
New Finding
 SCN9A mutations in paroxysmal extreme pain disorder: allelic variants underlie distinct channel defects and phenotypes.
Fertleman CR, Baker MD, …, Gardiner RM, Rees M
Neuron 2006 Dec 7 52(5):767-74 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Hanns Ulrich Zeilhofer / Massimo Pandolfo
First evaluation 9 Feb 2007 | Latest evaluation 27 Feb 2007

 
6
Exceptional
F1000 Factor 9.0

Confirmation
New Finding
 Dok-7 myasthenia: phenotypic and molecular genetic studies in 16 patients.
Selcen D, Milone M, …, Wieben ED, Engel AG
Ann Neurol 2008 Jul 64(1):71-87 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Richard Lewis
Evaluated 27 Nov 2008
 
7
Exceptional
F1000 Factor 9.0
Articles that inform your practice or change your way of thinking Changes
Clinical Practice

New Finding
 Impact of fever on outcome in patients with stroke and neurologic injury: a comprehensive meta-analysis.
Greer DM, Funk SE, …, Ouzounelli M, Uman GC
Stroke 2008 Nov 39(11):3029-35 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Donald Marion
Evaluated 18 Nov 2008
 
8
Exceptional
F1000 Factor 9.0

Confirmation
 Cranial Autonomic Symptoms in Migraine: Characteristics and Comparison with Cluster Headache.
Lai TH, Fuh JL, Wang SJ
J Neurol Neurosurg Psychiatry 2008 Oct 17 [abstract on PubMed] [related articles] [full text]
Selected by | David Dodick with Todd J Schwedt
Evaluated 14 Nov 2008
 
9
Exceptional
F1000 Factor 9.0

New Finding
 Non-cell-autonomous effects of presenilin 1 variants on enrichment-mediated hippocampal progenitor cell proliferation and differentiation.
Choi SH, Veeraraghavalu K, …, Ramirez JM, Sisodia SS
Neuron 2008 Aug 28 59(4):568-80 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Riqiang Yan
Evaluated 3 Oct 2008
 
10
Exceptional
F1000 Factor 9.0

New Finding
 Exposure to antipsychotics and risk of stroke: self controlled case series study.
Douglas IJ, Smeeth L
BMJ 2008 337:a1227 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Alistair Burns with Gregor Russell
Evaluated 25 Sep 2008

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